Department of Obstetrics and Gynaecology, Aga Khan University hospital, Nairobi, Kenya.
BMC Psychiatry. 2019 Jan 7;19(1):8. doi: 10.1186/s12888-018-1991-5.
Miscarriages are a common pregnancy complication and positive depression screen after a miscarriage has been shown to be high in our population. Various factors are associated with an increased risk of developing depression after a miscarriage. However, these factors vary across populations studied with no studies existing in our region. We set out to determine the factors associated with a positive depression screen among post-miscarriage women at the Aga Khan University hospital, Nairobi.
Patients were recruited at the 2 weeks clinic review after a miscarriage in the gynaecological clinics. They were screened using the Edinburgh postnatal depression scale for depression after a miscarriage. Analysis was done using Univariate and multivariate analysis to compare clinical variables between the screen - positive and screen - negative women in order to delineate the potential pattern of association between the two among the study subjects.
Positive depression screen was detected in 34.1% of the patients recruited. Univariate analysis revealed that education level (p = 0.039) and mode of conception (p = 0.005) impacted on the outcome of the depression screen. In multivariate analysis, multiple factors impacted on the depression screen and these included: age (p = 0.009), education level (p = 0.001), gestation at miscarriage (p = 0.04), marital status (p = 0.043), prior miscarriage (p = 0.011) and mode of conception (p = 0.03).
Factors that seem to impact on the positive depression screen include a younger age, low education level, an older gestational age at miscarriage, being single, an assisted mode of conception and prior miscarriage. These factors may be used to triage women after a miscarriage in order to pick up those who may screen positive for depression after a miscarriage.
流产是一种常见的妊娠并发症,在我们的人群中,流产后出现抑郁阳性筛查的比例很高。各种因素与流产后发生抑郁的风险增加有关。然而,这些因素在不同的研究人群中有所不同,我们所在地区尚无相关研究。我们旨在确定在肯尼亚阿迦汗大学医院流产后妇女中,与流产后抑郁阳性筛查相关的因素。
在妇科诊所流产后 2 周的诊所复查时,招募患者。他们使用爱丁堡产后抑郁量表筛查流产后的抑郁。使用单变量和多变量分析对阳性和阴性筛查妇女的临床变量进行比较,以描绘研究对象中两者之间潜在的关联模式。
招募的患者中有 34.1%检测到抑郁阳性筛查。单变量分析显示,教育水平(p=0.039)和受孕方式(p=0.005)对抑郁筛查结果有影响。多变量分析显示,多种因素对抑郁筛查有影响,包括:年龄(p=0.009)、教育水平(p=0.001)、流产时的孕龄(p=0.04)、婚姻状况(p=0.043)、既往流产史(p=0.011)和受孕方式(p=0.03)。
似乎影响抑郁阳性筛查的因素包括年龄较小、教育水平较低、流产时的孕龄较大、单身、辅助受孕方式和既往流产史。这些因素可用于对流产后的妇女进行分诊,以发现可能在流产后出现抑郁阳性筛查的妇女。