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巴亚蒙地区胰岛素依赖型糖尿病患者甲状腺自身免疫的患病率

Prevalence of thyroid autoimmunity in insulin dependent diabetes mellitus in the Bayamon region.

作者信息

Sánchez-Lugo F

机构信息

Universidad Central del Caribe, School of Medicine, Department of Pediatrics, Ramón Ruiz Arnau University Hospital.

出版信息

Bol Asoc Med P R. 1991 Feb;83(2):54-7.

PMID:2043229
Abstract

The purpose of this study was to describe our experience in the Bayamon region with respect to the prevalence of thyroid autoimmunity in our pediatric diabetic population. We identified a total of 78 patients with IDDM and all were examined to ascertain the presence of goiter. Thyroid profile, free thyroxine, thyrotropin, and thyroid microsomal autoantibodies were measured by radioimmunoassay in 65 of these patients. The data was analyzed using the Chi square test in order to correlate thyroid dysfunction with respect to sex and thyroid autoimmunity. Our results revealed a prevalence of thyroid autoimmunity in our IDDM patients of 15%, 40% of them had a goiter (p less than 001) and most of them were female (9 of 12). This is the lowest prevalence of thyroid autoimmunity in diabetic children reported in Hispanic groups in the United States thus far.

摘要

本研究的目的是描述我们在巴亚蒙地区儿科糖尿病患者群体中甲状腺自身免疫患病率方面的经验。我们共确定了78例胰岛素依赖型糖尿病(IDDM)患者,并对所有患者进行检查以确定是否存在甲状腺肿。其中65例患者通过放射免疫分析法检测了甲状腺功能指标、游离甲状腺素、促甲状腺激素和甲状腺微粒体自身抗体。使用卡方检验对数据进行分析,以便将甲状腺功能障碍与性别和甲状腺自身免疫相关联。我们的结果显示,IDDM患者中甲状腺自身免疫的患病率为15%,其中40%有甲状腺肿(p小于0.

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