Campbell P J, Chilton H W, Garvey P A, Gupta J M
Department of Newborn Care, Royal Hospital for Women, University of New South Wales, Australia.
J Paediatr Child Health. 1991 Feb;27(1):31-3. doi: 10.1111/j.1440-1754.1991.tb00341.x.
Six very low birthweight neonates with terminal respiratory failure due to severe hyaline membrane disease who failed to respond to conventional ventilation were offered a trial of high frequency jet ventilation using the volumetric diffusive respirator (VDR). All neonates showed improvement in pulmonary function. Two neonates were weaned successfully from high frequency ventilation. The results of this initial trial suggest that the volumetric diffusive respirator is a safe and effective method of ventilation in neonates with respiratory failure and that the survival rate in such neonates might be enhanced if treatment is introduced earlier in the disease.
六名因严重透明膜病导致终末期呼吸衰竭且对传统通气无反应的极低出生体重新生儿接受了使用容积扩散呼吸器（VDR）进行高频喷射通气的试验。所有新生儿的肺功能均有改善。两名新生儿成功撤离高频通气。这项初步试验的结果表明，容积扩散呼吸器是治疗呼吸衰竭新生儿的一种安全有效的通气方法，并且如果在疾病早期引入治疗，此类新生儿的存活率可能会提高。
