[5-氨基水杨酸所致急性胰腺炎]
[Acute pancreatitis due to 5-aminosalicylic acid].
作者信息
Romero Castro R, Jiménez Sáenz M, Pellicer Bautista F J, Domínguez Palomo S, Herrerías Gutiérrez J M
机构信息
Servicio de Gastroenterología, Hospital Universitario Virgen Macarena, Sevilla.
出版信息
Rev Esp Enferm Dig. 1991 Mar;79(3):219-21.
We report a case of a 5-aminosalicylate-induced pancreatitis in a patient with Crohn's disease. These findings suggest that some side effects, traditionally thought to be related to sulphafapyridine, are really due to 5-aminosalicylate. The good prognosis of this rare complication depends on the early withdrawal of the drug. Therefore the degree of the clinical suspicion plays a essential role in the appropriate diagnosis, but a challenge with mesalazine must be carried out in those patients in which other causes of pancreatitis could not be excluded.
我们报告了1例克罗恩病患者发生5-氨基水杨酸诱导的胰腺炎。这些发现表明，一些传统上认为与柳氮磺胺吡啶有关的副作用，实际上是由5-氨基水杨酸引起的。这种罕见并发症的良好预后取决于药物的早期停用。因此，临床怀疑程度在正确诊断中起着至关重要的作用，但对于那些无法排除其他胰腺炎病因的患者，必须进行美沙拉嗪激发试验。
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