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Coupled decomposition of four-dimensional NOESY spectra.耦合分解四维 NOESY 谱。
J Am Chem Soc. 2009 Sep 16;131(36):12970-8. doi: 10.1021/ja902012x.
2
The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating.小鼠电压依赖性阴离子通道1（VDAC1）在2.3埃分辨率下的晶体结构揭示了代谢物门控的机制。
Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17742-7. doi: 10.1073/pnas.0809634105. Epub 2008 Nov 6.
3
Structure of the human voltage-dependent anion channel.人类电压依赖性阴离子通道的结构。
Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15370-5. doi: 10.1073/pnas.0808115105. Epub 2008 Oct 1.
4
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.去污剂胶束中完整人膜蛋白VDAC-1的溶液结构。
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5
Mitochondrial membrane permeabilization in cell death.细胞死亡中的线粒体膜通透性改变
Physiol Rev. 2007 Jan;87(1):99-163. doi: 10.1152/physrev.00013.2006.
6
NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL.线粒体外膜蛋白电压依赖性阴离子通道（VDAC）的核磁共振结构研究及其与抗凋亡蛋白Bcl-xL的相互作用。
Biochemistry. 2007 Jan 16;46(2):514-25. doi: 10.1021/bi061577h.
7
VDAC: the channel at the interface between mitochondria and the cytosol.电压依赖性阴离子通道：线粒体与细胞质之间界面处的通道。
Mol Cell Biochem. 2004 Jan-Feb;256-257(1-2):107-15. doi: 10.1023/b:mcbi.0000009862.17396.8d.
8
Ile, Leu, and Val methyl assignments of the 723-residue malate synthase G using a new labeling strategy and novel NMR methods.采用新的标记策略和新型核磁共振方法对723个残基的苹果酸合酶G进行异亮氨酸、亮氨酸和缬氨酸甲基归属。
J Am Chem Soc. 2003 Nov 12;125(45):13868-78. doi: 10.1021/ja030345s.
9
A robust and cost-effective method for the production of Val, Leu, Ile (delta 1) methyl-protonated 15N-, 13C-, 2H-labeled proteins.一种用于生产缬氨酸、亮氨酸、异亮氨酸（δ1）甲基质子化的15N-、13C-、2H标记蛋白质的强大且经济高效的方法。
J Biomol NMR. 1999 Apr;13(4):369-74. doi: 10.1023/a:1008393201236.
10
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC.Bcl-2家族蛋白通过线粒体通道VDAC调节凋亡诱导因子细胞色素c的释放。
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人源整合膜蛋白VDAC-1的主链及内腔侧链甲基基团归属

Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1.

作者信息

Hiller Sebastian, Malia Thomas J, Garces Robert G, Orekhov Vladislav Y, Wagner Gerhard

机构信息

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.

出版信息

Biomol NMR Assign. 2010 Apr;4(1):29-32. doi: 10.1007/s12104-009-9194-0. Epub 2009 Nov 22.

DOI:10.1007/s12104-009-9194-0
PMID:20437141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2896003/
Abstract

The voltage dependent anion channel (VDAC) forms a channel for metabolites and nutrients in the outer membrane of mitochondria, and it is also involved in apoptotic pathways. Here, we report sequence-specific NMR assignments for the isoform 1 of human VDAC reconstituted in lauryldimethylamine oxide (LDAO) detergent micelles. The assignments were deposited in the BMRB data base with accession number 16381.

摘要

电压依赖性阴离子通道（VDAC）在线粒体外膜中形成代谢物和营养物质的通道，并且它也参与凋亡途径。在此，我们报告了在月桂基二甲基氧化胺（LDAO）去污剂胶束中重组的人VDAC同工型1的序列特异性核磁共振（NMR）归属。这些归属已存入BMRB数据库，登录号为16381。