Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Germany.
Acta Biomater. 2010 Oct;6(10):3815-23. doi: 10.1016/j.actbio.2010.04.020. Epub 2010 May 21.
Monoclinic tetracalcium phosphate (TTCP, Ca(4)(PO(4))(2)O), also known by the mineral name hilgenstockite, is formed in the (CaO-P(2)O(5)) system at temperatures>1300 degrees C. TTCP is the only calcium phosphate with a Ca/P ratio greater than hydroxyapatite (HA). It appears as a by-product in plasma-sprayed HA coatings and shows moderate reactivity and concurrent solubility when combined with acidic calcium phosphates such as dicalcium phosphate anhydrous (DCPA, monetite) or dicalcium phosphate dihydrate (DCPD, brushite). Therefore it is widely used in self-setting calcium phosphate bone cements, which form HA under physiological conditions. This paper aims to review the synthesis and properties of TTCP in biomaterials applications such as cements, sintered ceramics and coatings on implant metals.
单斜四方晶系磷酸四钙（TTCP，Ca(4)(PO(4))(2)O），又称矿物名希伦施托克石，在（CaO-P(2)O(5))系统中于>1300°C 的温度下形成。TTCP 是唯一一种 Ca/P 比大于羟基磷灰石（HA）的磷酸钙。它作为等离子喷涂 HA 涂层的副产物出现，并在与酸性磷酸钙（如无水磷酸二氢钙（DCPA，磷灰石）或二水磷酸二氢钙（DCPD，白磷钙石）结合时表现出中等的反应性和同时的溶解性。因此，它被广泛应用于自固化磷酸钙骨水泥中，在生理条件下形成 HA。本文旨在综述 TTCP 在生物材料中的应用，如水泥、烧结陶瓷和植入金属表面涂层等方面的合成和性能。
