Sparr S A, Jay M, Drislane F W, Venna N
Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461.
Brain. 1991 Apr;114 ( Pt 2):789-800. doi: 10.1093/brain/114.2.789.
In one of the seminal works on visual agnosia, Adler (1944, 1950) presented the case of a 22-yr-old woman who sustained carbon monoxide cerebral toxicity in the Cocoanut Grove nightclub diaster of 1942. We located this patient 40 yrs after injury and performed a detailed reevaluation. The patient demonstrated persistent deficits in visual recognition, characterized most prominently by defective recognition of elemental shape and form, associated with alexia, prosopagnosia, visuospatial disorientation and impaired visual imagery. Visual acuity, colour recognition, writing ability and verbal intelligence were relatively preserved. Isolated bilateral occipital injury was demonstrated by CT and MRI scanning. On comparison with previously reported cases, our results support the hypothesis that carbon monoxide toxicity can induce a visual agnosia of the apperceptive type with well defined characteristics, seldom seen with other types of cerebral injury. Prognosis for long-term recovery is poor.
在关于视觉失认症的开创性著作之一中，阿德勒（1944年，1950年）介绍了一名22岁女性的病例，该女性在1942年可可诺特格罗夫夜总会灾难中遭受了一氧化碳脑中毒。受伤40年后，我们找到了这名患者并进行了详细的重新评估。该患者表现出持续的视觉识别缺陷，最突出的特征是对基本形状和形态的识别缺陷，伴有失读症、面孔失认症、视觉空间定向障碍和视觉表象受损。视力、颜色识别、书写能力和语言智力相对保留。CT和MRI扫描显示双侧枕叶孤立性损伤。与先前报道的病例相比，我们的结果支持这样的假设，即一氧化碳中毒可诱发具有明确特征的感知型视觉失认症，这在其他类型的脑损伤中很少见。长期恢复的预后很差。
