Department of Family Practice, University of Alberta, Edmonton, Alberta, Canada.
Mol Nutr Food Res. 2010 Aug;54(8):1072-6. doi: 10.1002/mnfr.200900601.
To determine if daily supplementation of 2000 IU of vitamin D(3) is able to normalize the 25(OH)D(3) status in a nursing home population, a group particularly prone to Vitamin D insufficiency. A chart review was performed to retrospectively determine the 25(OH)D(3) level in each nursing home patient (N=68) who had received a minimum of 5 months of daily 2000 IU vitamin D(3) supplementation. 94.1% of nursing home residents had a 25(OH)D(3) level in excess of 80 nmol/L after a minimum of 5 months of daily 2,000 IU vitamin D(3) supplementation. No residents had 25(OH)D(3) levels in a toxic range. In order to improve health and well-being and to preclude preventable morbidity and mortality associated with 25(OH)D(3) insufficiency, all nursing home patients without contraindication should be routinely supplemented with (at minimum) 2000 IU of vitamin D(3) on a daily basis.
为了确定每天补充 2000IU 的维生素 D(3) 是否能够使养老院人群的 25(OH)D(3)水平正常化，这是一个特别容易出现维生素 D 不足的群体。进行了一项图表回顾，以回顾性地确定接受至少 5 个月每天 2000IU 维生素 D(3)补充的每位养老院患者（N=68）的 25(OH)D(3)水平。在接受至少 5 个月每天 2000IU 维生素 D(3)补充后，94.1%的养老院居民的 25(OH)D(3)水平超过 80nmol/L。没有居民的 25(OH)D(3)水平处于毒性范围。为了改善健康和幸福感，并预防与 25(OH)D(3)不足相关的可预防发病率和死亡率，所有没有禁忌症的养老院患者都应常规每天补充（至少）2000IU 的维生素 D(3)。
