Green Christopher F, Burgul Kirti, Armstrong David J
Pharmacy Department, Countess of Chester NHS Foundation Trust, Liverpool, UK.
Int J Pharm Pract. 2010 Apr;18(2):116-21.
Medication history-taking is recognised as a potential source of medication errors and is the subject of the first National Patient Safety Agency/National Institute for Health and Clinical Excellence Patient Safety Guidance. Medication lists are suggested as a way of improving medicines reconciliation, but, anecdotally, can falsely reassure prescribers that they have an accurate list of medicines if used in isolation.
Patients in possession of a medicines list on admission to hospital were approached as part of routine care. Data were collated regarding medication-history discrepancies, their source and whether a prescription amendment was made.
One hundred and twenty patients were reviewed and the median time for pharmacists to complete medicines reconciliation was 15 min. Eighty-three patients (69.2%) had only one medication list, 31 (26%) had two, five (4%) had three and one patient (0.8%) had four lists. In total, 447 discrepancies were identified of which 49 (11.0%) were initiated by the patient, including 32 (65.3%) to adjust a dosage regimen or not to comply with a dosing regime. For the 279 (62.4%) discrepancies attributable to secondary care staff, 119 (42.6%) prescribed medicines were omitted unintentionally. For the 119 (26.6%) discrepancies attributable to the primary care medicines lists, 48 (40.3%) related to inadequate or inaccurate information regarding medicine doses, frequency, strength or form. Each patient required a mean of 1.6 amendments to their prescription despite bringing a list of medicines with them.
Medication lists should be interpreted with caution and assessed in combination with other sources of information, particularly the patient or their carer. Strategies to improve medicines reconciliation on admission to hospital are still needed and a single electronic patient record encompassing primary and secondary care medication records would be a positive step forward.
用药史采集被认为是用药错误的一个潜在来源,并且是首个国家患者安全机构/国家卫生与临床优化研究所患者安全指南的主题。用药清单被建议作为改善用药核对的一种方式,但据传闻,如果单独使用,可能会让开处方者错误地确信他们拥有准确的用药清单。
作为常规护理的一部分,对入院时持有用药清单的患者进行了研究。整理了有关用药史差异、其来源以及是否进行了处方修改的数据。
对120名患者进行了评估,药剂师完成用药核对的中位时间为15分钟。83名患者(69.2%)仅有一份用药清单,31名(26%)有两份,5名(4%)有三份,1名患者(0.8%)有四份清单。总共发现了447处差异,其中49处(11.0%)由患者引发,包括32处(65.3%)是为了调整用药方案或不遵守给药方案。对于279处(62.4%)归因于二级护理人员的差异,119处(42.6%)所开的药物被无意遗漏。对于119处(26.6%)归因于初级护理用药清单的差异,48处(40.3%)与药物剂量、频率、强度或剂型方面的信息不足或不准确有关。尽管患者带来了用药清单,但每位患者的处方平均需要1.6次修改。
对用药清单应谨慎解读,并结合其他信息来源进行评估(特别是患者或其护理人员提供的信息)。仍需要采取策略来改善入院时的用药核对,而涵盖初级和二级护理用药记录的单一电子患者记录将是向前迈出的积极一步。