School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland.
Centre for Innovative Human Systems & School of Psychology, Trinity College Dublin, Dublin, Ireland.
BMC Med Inform Decis Mak. 2021 Nov 3;21(1):307. doi: 10.1186/s12911-021-01659-8.
Medication reconciliation (MedRec), a process to reduce medication error at care transitions, is labour- and resource-intensive and time-consuming. Use of Personal Electronic Records of Medications (PERMs) in health information systems to support MedRec have proven challenging. Relatively little is known about the design, use or implementation of PERMs at care transitions that impacts on MedRec in the 'real world'. To respond to this gap in knowledge we undertook a rapid realist review (RRR). The aim was to develop theories to explain how, why, when, where and for whom PERMs are designed, implemented or used in practice at care transitions that impacts on MedRec.
We used realist methodology and undertook the RRR between August 2020 and February 2021. We collaborated with experts in the field to identify key themes. Articles were sourced from four databases (Pubmed, Embase, CINAHL Complete and OpenGrey) to contribute to the theory development. Quality assessment, screening and data extraction using NVivo was completed. Contexts, mechanisms and outcomes configurations were identified and synthesised. The experts considered these theories for relevance and practicality and suggested refinements.
Ten provisional theories were identified from 19 articles. Some theories relate to the design (T2 Inclusive design, T3 PERMs complement existing good processes, T7 Interoperability), some relate to the implementation (T5 Tailored training, T9 Positive impact of legislation or governance), some relate to use (T6 Support and on-demand training) and others relate iteratively to all stages of the process (T1 Engage stakeholders, T4 Build trust, T8 Resource investment, T10 Patients as users of PERMs).
This RRR has allowed additional valuable data to be extracted from existing primary research, with minimal resources, that may impact positively on future developments in this area. The theories are interdependent to a greater or lesser extent; several or all of the theories may need to be in play to collectively impact on the design, implementation or use of PERMs for MedRec at care transitions. These theories should now be incorporated into an intervention and evaluated to further test their validity.
药物重整(MedRec)是减少医疗交接过程中药物错误的一个流程,它需要大量的人力和资源,且耗时较长。在健康信息系统中使用个人电子药物记录(PERMs)来支持 MedRec 已经被证明具有挑战性。在“现实世界”中,关于在医疗交接过程中影响 MedRec 的 PERMs 的设计、使用或实施的相对较少。为了应对这一知识空白,我们进行了快速现实主义审查(RRR)。目的是开发理论来解释 PERMs 在医疗交接中的设计、实施或使用是如何、为什么、何时、何地以及为谁进行的,这些因素会对 MedRec 产生影响。
我们使用现实主义方法,于 2020 年 8 月至 2021 年 2 月进行了 RRR。我们与该领域的专家合作,确定了关键主题。文章来源于四个数据库(Pubmed、Embase、CINAHL Complete 和 OpenGrey),以促进理论发展。使用 NVivo 完成了质量评估、筛选和数据提取。确定了上下文、机制和结果配置,并进行了综合分析。专家们考虑了这些理论的相关性和实用性,并提出了改进建议。
从 19 篇文章中确定了 10 个临时理论。一些理论与设计有关(T2 包容性设计、T3 PERMs 补充现有良好流程、T7 互操作性),一些理论与实施有关(T5 量身定制的培训、T9 立法或治理的积极影响),一些理论与使用有关(T6 支持和按需培训),还有一些理论与整个过程的所有阶段都有关联(T1 让利益相关者参与进来、T4 建立信任、T8 资源投入、T10 患者是 PERMs 的使用者)。
这项 RRR 从现有初级研究中提取了更多有价值的数据,而且资源投入较少,这可能会对该领域的未来发展产生积极影响。这些理论在一定程度上是相互依存的;可能需要多个或所有理论共同发挥作用,才能对医疗交接过程中的 PERMs 的设计、实施或使用产生集体影响。这些理论现在应该被纳入干预措施并进行评估,以进一步检验其有效性。