Dahlöf C
Department of Clinical Pharmacology, Sahlgrenska Hospital, Gothenburg, Sweden.
Clin Cardiol. 1991 Feb;14(2):97-103. doi: 10.1002/clc.4960140204.
Quality of life is often considered to equate how the medical treatment is subjectively perceived by the patient, but ought to include the total impact of the disease/treatment on the patient's emotional, physical, and social well-being. Recently, a proposal for a generally applicable definition of quality of life in health care was put forward. This definition includes general well-being, health, and welfare (external factors), as three fundamental components, and the definition is based on both objective and subjective judgments. General well-being is exclusively and expression of the individual's subjective experience and is based on his or her own qualitative evaluation of well-being in relation to condition, treatments, and experiences. Health is according to the proposed definition, judged both objectively (signs) and subjectively (symptoms). Apart from health and well-being, there is also reason to include objectively registrable factors at the welfare level (external factors) such as the consumption of medicines, number of days in hospital, length of sick leave, need of in-home care, etc. This review is an attempt to elucidate the effects of antihypertensive pharmacotherapy on the patient's general well-being. The topic will be discussed from several points of views (e.g., aims of antihypertensive treatment, occurrence of symptoms in the population, compliance with prescribed treatment, symptom inventories, the concept of quality of life.
生活质量通常被认为等同于患者对医疗治疗的主观感受,但应该包括疾病/治疗对患者情感、身体和社会福祉的总体影响。最近,有人提出了一个适用于医疗保健中生活质量的通用定义。这个定义包括总体福祉、健康和福利(外部因素)这三个基本组成部分,并且该定义基于客观和主观判断。总体福祉完全是个人主观体验的一种表达,基于他或她自己对与状况、治疗和经历相关的福祉的定性评估。根据提议的定义,健康既要从客观(体征)也要从主观(症状)方面进行判断。除了健康和福祉之外,还有理由在福利层面(外部因素)纳入可客观记录的因素,如药物消费、住院天数、病假时长、家庭护理需求等。本综述旨在阐明抗高血压药物治疗对患者总体福祉的影响。将从几个角度讨论这个话题(例如,抗高血压治疗的目标、人群中症状的发生、对规定治疗的依从性、症状清单、生活质量的概念)。