Division of Arthroplasty, Mount Sinai Hospital, Toronto, ON, Canada.
Int Orthop. 2011 May;35(5):661-6. doi: 10.1007/s00264-010-1030-8. Epub 2010 May 5.
Patients with Down's syndrome (DS) have an increased incidence of coxarthrosis which may become symptomatic with prolonged life expectancy. We present seven consecutive patients (nine hips) with DS who had primary total hip arthroplasty (THA). Average clinical and radiological follow-up was 9.9 ± 6.4 years (range 2-22.25). Harris hip scores (HHS) improved significantly (p < 0.01) from 41.1 (range 18.5-65) to 80.2 (range 67.5-91) at latest follow-up. Two patients required revision arthroplasty for stem loosening at 16 (osteolysis) and six years (trauma) following THA, respectively. Six of the THAs required a constrained liner. No dislocations or deep infections were encountered. We contend that THA is a reliable surgical intervention in patients with DS and may be performed in symptomatic patients.
唐氏综合征(DS)患者的髋关节病发生率增加,随着预期寿命的延长,可能会出现症状。我们介绍了 7 例连续的 DS 患者(9 髋)行初次全髋关节置换术(THA)。平均临床和放射学随访时间为 9.9 ± 6.4 年(范围 2-22.25)。哈里斯髋关节评分(HHS)在末次随访时显著改善(p < 0.01),从 41.1(范围 18.5-65)增加到 80.2(范围 67.5-91)。2 例患者分别在 THA 后 16 年(骨溶解)和 6 年(创伤)因柄松动而需要翻修关节置换术。6 例 THA 需要使用约束衬垫。未发生脱位或深部感染。我们认为,THA 是 DS 患者可靠的手术干预措施,可对有症状的患者进行。