The Brain Dynamics Centre, Westmead Millennium Institute and University of Sydney, Westmead Hospital, Australia.
Eur Eat Disord Rev. 2010 May;18(3):165-79. doi: 10.1002/erv.974.
We reviewed the evidence for emotion-related disturbances in anorexia nervosa (AN) from behavioural, cognitive, biological and genetic domains of study. These domains were brought together within the framework of an integrative neuroscience model that emphasizes the role of emotion and feeling and their regulation, in brain organization. PsychInfo and Medline searches were performed to identify published peer-reviewed papers on AN within each domain. This review revealed evidence for 'Emotion', 'Thinking and Feeling' and 'Self-regulation' disturbances in AN that span non-conscious to conscious processes. An integrative neuroscience framework was then applied to develop a model of AN, from which hypotheses for empirical investigation are generated. We propose that AN reflects a core disturbance in emotion at the earliest time stage of information processing with subsequent effects on the later stages of thinking, feeling and self-regulation.
我们回顾了厌食症（AN）在行为、认知、生物和遗传研究领域中与情绪相关的障碍的证据。这些领域在一个强调情绪和感觉及其调节在大脑组织中的作用的综合神经科学模型框架内结合在一起。在每个领域中，我们都在 PsychInfo 和 Medline 上进行了搜索，以确定关于 AN 的已发表的同行评审论文。这一综述揭示了厌食症中存在“情绪”、“思考和感觉”以及“自我调节”障碍的证据，这些障碍跨越了无意识到有意识的过程。然后，我们应用综合神经科学框架来建立一个厌食症模型，从中生成了用于实证研究的假设。我们提出，厌食症反映了信息处理的最早阶段的核心情绪障碍，随后对思考、感觉和自我调节的后期阶段产生影响。
