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经迷路入路切除大型或巨大型前庭神经鞘瘤后的围手术期并发症:123例患者的结果

Perioperative complications after translabyrinthine removal of large or giant vestibular schwannoma: Outcomes for 123 patients.

作者信息

Charpiot Anne, Tringali Stéphane, Zaouche Sandra, Ferber-Viart Chantal, Dubreuil Christian

机构信息

Département d'Otologie et d'Otoneurochirurgie, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.

出版信息

Acta Otolaryngol. 2010 Nov;130(11):1249-55. doi: 10.3109/00016481003762316.

Abstract

CONCLUSION

Large vestibular schwannomas are benign but dangerous tumors. The translabyrinthine approach allows the surgeon to limit vital and functional complications due to the disease itself or to its surgical removal.

OBJECTIVE

Morbi-mortality study focused on large vestibular schwannoma surgically treated by translabyrinthine removal.

METHODS

This was a retrospective review of prospectively collected data in a series of 123 patients who underwent translabyrinthine removal of a large vestibular schwannoma (>4 cm in the cerebellopontine angle, stage IV). All surgical and medical complications and facial function were reviewed, with a 1-year follow-up.

RESULTS

Mortality during the first year was 0.8% (one case of infarct of the anterior inferior cerebellar artery, fatal after 8 months). In all, 4.9% of patients underwent a second surgery (for delayed hemorrhage or cerebrospinal fluid leak) during the first months after removal of a large vestibular schwannoma; 3.2% of patients experienced definitive neurologic complications (one death, one cerebellar disturbance, and two cases of 10th cranial nerve palsy).

摘要

结论

大型前庭神经鞘瘤是良性但危险的肿瘤。经迷路入路可使外科医生减少因疾病本身或手术切除导致的重要和功能并发症。

目的

对经迷路切除术治疗大型前庭神经鞘瘤的手术死亡率进行研究。

方法

这是一项对前瞻性收集数据的回顾性研究,该系列研究纳入了123例行经迷路切除大型前庭神经鞘瘤(桥小脑角区肿瘤直径>4 cm,IV期)的患者。回顾了所有手术和医疗并发症以及面神经功能,并进行了为期1年的随访。

结果

第一年的死亡率为0.8%(1例小脑前下动脉梗死,8个月后死亡)。总共4.9%的患者在大型前庭神经鞘瘤切除后的头几个月内接受了二次手术(因迟发性出血或脑脊液漏);3.2%的患者出现了确定性神经并发症(1例死亡,1例小脑功能障碍,2例第10对脑神经麻痹)。

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