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预防经迷路切除前庭神经鞘瘤后脑脊液漏

Prevention of cerebrospinal fluid leak after translabyrinthine resection of vestibular schwannoma.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, U.S.A.

出版信息

Otol Neurotol. 2010 Apr;31(3):473-7. doi: 10.1097/MAO.0b013e3181cdd8fc.

DOI:10.1097/MAO.0b013e3181cdd8fc
PMID:20084041
Abstract

OBJECTIVE

Evaluate the rate of cerebrospinal fluid (CSF) leak after translabyrinthine craniotomy for the removal of vestibular schwannoma and describe details of closure technique.

STUDY DESIGN

Retrospective case review.

SETTING

Tertiary referral center.

PATIENTS

All individuals undergoing translabyrinthine craniotomy for removal of vestibular schwannoma from January 2000 to October 2008.

INTERVENTION

Translabyrinthine craniotomy for removal of vestibular schwannoma with abdominal fat graft harvest and layered closure.

MAIN OUTCOME MEASURES

Presence of cerebrospinal fluid leak and need for additional surgeries or medical interventions.

RESULTS

Sixty-one patients underwent translabyrinthine craniotomy for the removal of vestibular schwannoma during a 9-year period. None of the patients had a CSF leak in the immediate postoperative period or during the mean follow-up period of 31.3 months.

CONCLUSION

Successful wound closure and CSF leak prevention after translabyrinthine craniotomy for the removal of vestibular schwannomas do not require the creation of a facial recess, manipulation of the ossicles, direct Eustachian tube plugging, or the use of alloplastic space-occupying materials. The closure technique used in the current study has proven effective over time with no evidence of CSF leak among patients seen in follow-up.

摘要

目的

评估经迷路颅底手术切除前庭神经鞘瘤后发生脑脊液(CSF)漏的比率,并描述关闭技术的细节。

研究设计

回顾性病例研究。

设置

三级转诊中心。

患者

2000 年 1 月至 2008 年 10 月期间因前庭神经鞘瘤而行迷路颅底手术的所有患者。

干预措施

经迷路颅底手术切除前庭神经鞘瘤,同时进行腹部脂肪移植物采集和分层关闭。

主要观察指标

CSF 漏的存在以及是否需要额外的手术或医疗干预。

结果

在 9 年期间,有 61 例患者因前庭神经鞘瘤而行迷路颅底手术。在术后即刻或平均 31.3 个月的随访期间,均无患者发生 CSF 漏。

结论

成功关闭迷路颅底手术切口并预防 CSF 漏,无需创建面神经隐窝、操作听骨、直接填塞咽鼓管,或使用同种异体占位性材料。在本研究中使用的关闭技术已被证明是有效的,在随访的患者中没有 CSF 漏的证据。

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