Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Arch Dis Child Fetal Neonatal Ed. 2010 May;95(3):F201-5. doi: 10.1136/adc.2009.160614.
To compare trajectories for growth and somatic health characteristics until adulthood of non-handicapped low birthweight (LBW) and normal birthweight (NBW) children.
Population-based longitudinal follow-up study.
LBW (<2 kg) and NBW (>3 kg) children were followed at 5, 11 and 19 years of age. At 19 years 134 of 173 subjects with LBW (77%), and 135 of the 170 with NBW (79%) participated.
Current health and body mass index (BMI) were similar for the groups. The LBW adults were shorter (5.9 cm), had higher systolic (4.5 mm Hg) and diastolic (2.0 mm Hg) blood pressures (BPs), higher heart rates (3.7 beats per min), lower forced expiratory flow at 50% of forced vital capacity (8.5%) and forced expiratory volume in 1 second/forced vital capacity ratios (0.03). All p values are <0.01 for the differences of means given above. Differences in height were mostly due to differences in parental height. From childhood, percentiles for height and systolic BP were maintained for both groups while diastolic BP increased more for the LBW children. The LBW young adults caught up in body proportions.
Difference in height and systolic BP between the LBW and NBW children tend to be maintained from childhood until young adulthood. The LBW young adults experience catch-up growth in body proportions. The LBW young adults have lower pulmonary function.
比较非残疾低出生体重(LBW)和正常出生体重(NBW)儿童直至成年的生长和身体健康特征轨迹。
基于人群的纵向随访研究。
LBW(<2 公斤)和 NBW(>3 公斤)儿童在 5、11 和 19 岁时进行随访。19 岁时,173 名 LBW 受试者中有 134 名(77%)和 170 名 NBW 受试者中有 135 名(79%)参与了研究。
两组的当前健康状况和体重指数(BMI)相似。LBW 成年人身高较矮(5.9 厘米),收缩压(4.5 毫米汞柱)和舒张压(2.0 毫米汞柱)较高,心率(3.7 次/分钟)较快,用力呼气量在 50%用力肺活量时较低(8.5%),用力呼气量/用力肺活量比值较低(0.03)。上述所有差异的均值均具有统计学意义(p 值均<0.01)。身高差异主要归因于父母身高的差异。从儿童期开始,两组的身高和收缩压百分位数都得到了维持,而 LBW 儿童的舒张压则有所增加。LBW 年轻人在身体比例方面实现了追赶生长。
LBW 和 NBW 儿童之间的身高和收缩压差异从儿童期到青年期趋于保持。LBW 年轻人在身体比例方面经历了追赶生长。LBW 年轻人的肺功能较低。