Duncan I D, Amundson J, Cuddon P A, Sufit R, Jackson K F, Lindsay W A
Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706.
Equine Vet J. 1991 Mar;23(2):94-8. doi: 10.1111/j.2042-3306.1991.tb02728.x.
The laryngeal muscles of 18 horses were examined histologically. The neurogenic changes found in each muscle were scored by four reviewers and the results evaluated statistically. Fifteen of these horses had endoscopic evidence of abnormal laryngeal function, three of which were defined as having adductor paralysis. Measurement of muscle fibre area in two horses with idiopathic laryngeal hemiplegia (ILH) was performed. In the quantitative study of neurogenic change, the adductor muscles were more significantly affected than the abductor muscle. This was also true in the clinical cases of ILH where measurement of muscle fibre area demonstrated that the lateral cricoarytenoid (adductor) muscles showed a wider range of pathological changes than the dorsal cricoarytenoid muscle (abductor). Those horses with the most severe muscle pathology also had the most abnormal endoscopic findings. The propensity for denervation of the adductor muscles should provide clues as to the pathogenesis and natural history of horses with sub-clinical laryngeal disease and ILH.
对18匹马的喉部肌肉进行了组织学检查。四名评估人员对每块肌肉中发现的神经源性变化进行评分，并对结果进行统计学评估。其中15匹马有喉镜检查显示喉部功能异常的证据，其中3匹被定义为内收肌麻痹。对两匹患有特发性喉偏瘫（ILH）的马进行了肌纤维面积测量。在神经源性变化的定量研究中，内收肌比外展肌受影响更显著。在ILH临床病例中也是如此，肌纤维面积测量显示，环杓侧肌（内收肌）的病理变化范围比环杓后肌（外展肌）更广。那些肌肉病变最严重的马，其喉镜检查结果也最异常。内收肌去神经支配的倾向应为亚临床喉部疾病和ILH马匹的发病机制及自然史提供线索。
