Department of Applied Health Science, Indiana University, HPER Building 116, 1025 East 7th Street, Bloomington, IN 47405-4801, USA.
J Epidemiol Community Health. 2010 May;64(5):426-31. doi: 10.1136/jech.2009.089680.
It is not well established whether total volume of leisure-time physical activity (LTPA) has dose-response effects on obesity.
The dose-response relationship was examined using 12 227 non-institutionalised individuals, aged 20-64 years, drawn from the 8 years (1999-2006) of the continuous National Health and Nutrition Examination Survey (NHANES), a nationally representative sample of the US population.
The age-adjusted prevalence of women's obesity was 41.4% for those with no LTPA in the past month; 39.1% for those who engaged in LTPA but fell short of the recommended minimum amount of LTPA (ie, <450 metabolic equivalent minutes per week (MET min/week)); 31.0% for those who met the recommended minimum guideline (ie, 450 to < 750); 28.0% for those whose LTPA exceeded the minimum guideline but less than the first quartile among the overachievers (ie, 750 to <1260); 23.4% for the overachievers between the first and third quartile (ie, 1260 to <3556); and 19.5% for the overachievers at or above the third quartile (ie, 3556 MET min/week or above). This association was maintained even after occupational physical activity (OPA) was controlled. However, this pattern was not observed for Mexican and black adults and showed a floor effect as LTPA increased.
There is a crude graded inverse dose-response relationship between total volume of LTPA and obesity in US adult women, but not in men. Gender and racial/ethnic differences exist in the relationship of accumulated LTPA with obesity due, in part, to differential ratios of LTPA to OPA.
休闲时间体力活动（LTPA）总量对肥胖的影响是否存在剂量反应关系尚未得到很好的证实。
本研究使用了 1999 年至 2006 年持续开展的 8 年全国健康与营养调查（NHANES）中的 12227 名 20-64 岁的非机构化个体，该调查为美国人群的全国代表性样本，分析了这种剂量反应关系。
在调整年龄后，过去一个月没有进行任何 LTPA 的女性肥胖患病率为 41.4%；进行了 LTPA 但未达到推荐的最低 LTPA 量（即<450 代谢当量分钟/周（MET min/周））的女性肥胖患病率为 39.1%；达到推荐的最低指导量（即 450 至<750）的女性肥胖患病率为 31.0%；LTPA 超过最低指导量但低于超量活动者的第一个四分位数（即 750 至<1260）的女性肥胖患病率为 28.0%；超量活动者处于第一和第三个四分位数之间（即 1260 至<3556）的女性肥胖患病率为 23.4%；超量活动者达到或超过第三个四分位数（即 3556 MET min/周或以上）的女性肥胖患病率为 19.5%。即使控制了职业体力活动（OPA），这种关联仍然存在。然而，这种模式在墨西哥裔和非裔美国成年人中并未观察到，并且随着 LTPA 的增加出现了一个下限效应。
在美国成年女性中，总 LTPA 量与肥胖之间存在粗略的分级反向剂量反应关系，但在男性中则不然。由于 LTPA 与 OPA 的比例不同，性别和种族/民族差异存在于 LTPA 与肥胖的关系中。
