Itoh A, Okubo S, Nakanishi N, Yoshioka T, Kunieda T, Kosakai Y, Kito Y, Yutani C
Division of Cardiology, National Cardiovascular Center, Osaka, Japan.
Eur Heart J. 1991 Feb;12(2):270-2. doi: 10.1093/oxfordjournals.eurheartj.a059879.
Primary malignant tumours of the heart are very rare, with an incidence of only 0.0017%-0.03% in consecutive autopsy series. Fibrosarcoma of the heart is also rare, representing only about 0.3% of all cardiac tumours. We observed a case of epicardial fibrosarcoma which developed 12 years after the first resection of an epicardial tumour. A 31-year-old woman was referred to our hospital because of fatigue, nausea and right back pain. She had had surgery to resect an epicardial tumour when she was 19 years old. On admission, there was a huge, heterogeneous tumour on the right inferior side of the heart. At surgery, the tumour was totally resected and a pathological diagnosis of fibrosarcoma was made. The patient was free of symptoms for 6 months, but died of a recurrence 11 months after the operation. It is postulated that the epicardial tumour had only been partially resected and had been latent for a rather long period but began to grow rapidly 12 years after the initial resection.
原发性心脏恶性肿瘤非常罕见，在连续尸检系列中的发病率仅为0.0017% - 0.03%。心脏纤维肉瘤也很罕见，仅占所有心脏肿瘤的约0.3%。我们观察到一例心外膜纤维肉瘤病例，该病例在首次切除心外膜肿瘤12年后发生。一名31岁女性因疲劳、恶心和右背痛被转诊至我院。她19岁时曾接受过心外膜肿瘤切除术。入院时，心脏右下侧有一个巨大的、异质性肿瘤。手术中，肿瘤被完全切除，并做出了纤维肉瘤的病理诊断。患者无症状6个月，但术后11个月死于复发。据推测，心外膜肿瘤当初仅被部分切除，并潜伏了相当长一段时间，但在初次切除12年后开始迅速生长。
