SATIE, ENS-Cachan Bretagne, CNRS, UEB, av Robert Schuman, F-35170 Bruz, France.
Lab Chip. 2010 Jul 21;10(14):1835-40. doi: 10.1039/c001900c. Epub 2010 May 5.
We report a novel method for bubble or droplet displacement, capture and switching within a bifurcation channel for applications in digital microfluidics based on the Marangoni effect, i.e. the appearance of thermocapillary tangential interface stresses stemming from local surface tension variations. The specificity of the reported actuation is that heating is provided by an optimized resistor pattern (B. Selva, J. Marchalot and M.-C. Jullien, An optimized resistor pattern for temperature gradient control in microfluidics, J. Micromech. Microeng., 2009, 19, 065002) leading to a constant temperature gradient along a microfluidic cavity. In this context, bubbles or droplets to be actuated entail a surface force originating from the thermal Marangoni effect. This actuator has been characterized (B. Selva, I. Cantat, and M.-C. Jullien, Migration of a bubble towards a higher surface tension under the effect of thermocapillary stress, preprint, 2009) and it was found that the bubble/droplet (called further element) is driven toward a high surface tension region, i.e. toward cold region, and the element velocity increases while decreasing the cavity thickness. Taking advantage of these properties three applications are presented: (1) element displacement, (2) element switching, detailed in a given range of working, in which elements are redirected towards a specific evacuation, (3) a system able to trap, and consequently stop on demand, the elements on an alveolus structure while the continuous phase is still flowing. The strength of this method lies in its simplicity: single layer system, in situ heating leading to a high level of integration, low power consumption (P < 0.4 W), low applied voltage (about 10 V), and finally this system is able to manipulate elements within a flow velocity up to 1 cm s(-1).
我们报告了一种在分岔通道内实现气泡或液滴置换、捕获和切换的新方法,该方法基于 Marangoni 效应,即源自局部表面张力变化的热毛细切向界面应力的出现,应用于基于数字微流控的技术中。所报告的致动的特殊性在于,通过优化的电阻器图案(B. Selva、J. Marchalot 和 M.-C. Jullien,An optimized resistor pattern for temperature gradient control in microfluidics,J. Micromech. Microeng.,2009,19,065002)提供加热,从而沿微流腔产生恒定的温度梯度。在这种情况下,要进行操作的气泡或液滴需要源自热 Marangoni 效应的表面力。该致动器已经过表征(B. Selva、I. Cantat 和 M.-C. Jullien,Migration of a bubble towards a higher surface tension under the effect of thermocapillary stress,preprint,2009),并且发现气泡/液滴(进一步称为元件)被驱动到具有较高表面张力的区域,即冷区域,并且元件速度随着腔厚度的减小而增加。利用这些特性,展示了三种应用:(1)元件位移,(2)元件切换,在特定工作范围内详细说明,其中元件被重新引导到特定的排空,(3)一种能够在连续相仍在流动时捕获并按需停止肺泡结构上的元件的系统。该方法的优点在于其简单性:单层系统,原位加热可实现高度集成,低功耗(P <0.4 W),低应用电压(约 10 V),最后,该系统能够在流速高达 1 cm s(-1)的情况下操纵元件。