Remmelink H J, Hoeke A
Orthodontistenpraktijk Almelo.
Ned Tijdschr Tandheelkd. 2010 Apr;117(4):227-31. doi: 10.5177/ntvt2010.04.09133.
The obstructive sleep apnea syndrome (OSAS) is characterized by repetitive upper airway obstructions during sleep. This sleep-related breathing disorder is associated with excessive daytime sleepiness and increased cardiovascular risk. Recently, the national multidisciplinary guidelines for the diagnosis and treatment of OSAS in adults have been thoroughly revised. In the guidelines an important place has been created for mandibular repositioning appliances. With these devices, which resemble activators, a widening of the upper airways is produced during sleep by advancing the mandible. According to the guidelines therapy with repositioning appliances should be considered a first-line treatment for patients with mild to moderate OSAS.
阻塞性睡眠呼吸暂停综合征（OSAS）的特征是睡眠期间反复出现上呼吸道阻塞。这种与睡眠相关的呼吸障碍与白天过度嗜睡和心血管风险增加有关。最近，成人OSAS诊断和治疗的国家多学科指南已被彻底修订。在这些指南中，下颌重新定位矫治器占据了重要地位。使用这些类似矫治器的装置，通过前移下颌在睡眠期间可使上呼吸道变宽。根据指南，对于轻度至中度OSAS患者，应将使用重新定位矫治器进行治疗视为一线治疗方法。
