Mickelson Samuel A
Advanced Ear, Nose & Throat Associates, The Atlanta Snoring and Sleep Disorders Institute, 960 Johnson Ferry Road NE, Suite 200, Atlanta, GA 30342, USA.
Otolaryngol Clin North Am. 2020 Jun;53(3):397-407. doi: 10.1016/j.otc.2020.02.004. Epub 2020 Mar 26.
Obstructive sleep apnea is a common condition, caused primarily by narrowing of the nasal and pharyngeal airway, leading to partial or complete airway collapse during sleep. Treatment with positive airway pressure (PAP) is considered first-line therapy, due to an efficacy rate of approximately 95%, yet long-term compliance with PAP is less than 40%. The efficacy of a sleep oral appliance is lower than PAP, yet it may have similar effectiveness. A sleep oral appliance is a reasonable second-line therapy for patients who refuse or fail PAP and may be reasonable first-line therapy.
阻塞性睡眠呼吸暂停是一种常见病症，主要由鼻腔和咽部气道变窄引起，导致睡眠期间气道部分或完全塌陷。持续气道正压通气（PAP）治疗被视为一线治疗方法，因其有效率约为95%，然而长期坚持使用PAP的比例不到40%。睡眠口腔矫治器的疗效低于PAP，但可能具有相似的效果。对于拒绝使用PAP或使用PAP失败的患者，睡眠口腔矫治器是一种合理的二线治疗方法，也可能是合理的一线治疗方法。
