Kurosawa S, Ogura A, Koura M, Noguchi A, Noguchi Y, Yamamoto Y, Takano K
Department of Veterinary Science, National Institute of Health, Tokyo, Japan.
Jikken Dobutsu. 1991 Apr;40(2):259-61. doi: 10.1538/expanim1978.40.2_259.
Light microscopic examinations were done on the skin and hairs of PC (poor coat) mice, maintained as an inbred strain at the National Institute of Health, Japan. The structures of the epidermis, dermis, hair root sheath and the sebaceous glands were normal. Hair bulbs and hair papillae were poorly developed at anagen stage of hair cycle. Having scanty medulla, the hairs were thin and short. The hair cuticle appeared normal. These findings suggest that the defective hair growth in PC mice is caused by deficiencies in cell differentiation and/or proliferation in the hair matrix.
对作为近交系保存在日本国立卫生研究院的PC（被毛不良）小鼠的皮肤和毛发进行了光学显微镜检查。表皮、真皮、毛根鞘和皮脂腺的结构正常。在毛发周期的生长期，毛球和毛乳头发育不良。髓质稀少，毛发又细又短。毛小皮看起来正常。这些发现表明，PC小鼠毛发的生长缺陷是由毛基质中细胞分化和/或增殖不足引起的。
