College of Life Science, Northwest Normal University, Lanzhou, 730070, China.
Mol Plant Pathol. 2010 May;11(3):429-40. doi: 10.1111/j.1364-3703.2010.00615.x.
To survive, plants possess elaborate defence mechanisms to protect themselves against virus or pathogen invasion. Recent studies have suggested that plant mitochondria may play an important role in host defence responses to biotic stresses. In contrast with animal mitochondria, plant mitochondria possess a unique respiratory pathway, the cyanide-insensitive alternative pathway, which is catalysed by the alternative oxidase (AOX). Much work has revealed that the genes encoding AOX, AOX protein and the alternative respiratory pathway are frequently induced during plant-pathogen (or virus) interaction. This raises the possibility that AOX is involved in host defence responses to biotic stresses. Thus, a key to the understanding of the role of mitochondrial respiration under biotic stresses is to learn the function and regulation of AOX. In this article, we focus on the theoretical and experimental progress made in the current understanding of the function and regulation of AOX under biotic stresses. We also address some speculative aspects to aid further research in this area.
为了生存，植物拥有复杂的防御机制来保护自己免受病毒或病原体的侵害。最近的研究表明，植物线粒体可能在宿主对生物胁迫的防御反应中发挥重要作用。与动物线粒体不同，植物线粒体拥有独特的呼吸途径，即氰化物不敏感的替代途径，该途径由交替氧化酶（AOX）催化。大量研究表明，编码 AOX、AOX 蛋白和替代呼吸途径的基因在植物-病原体（或病毒）相互作用过程中经常被诱导。这就提出了 AOX 可能参与宿主对生物胁迫的防御反应的可能性。因此，理解生物胁迫下线粒体呼吸作用的关键是了解 AOX 的功能和调控。在本文中，我们重点介绍了在当前理解生物胁迫下 AOX 的功能和调控方面所取得的理论和实验进展。我们还讨论了一些推测性的方面，以帮助该领域的进一步研究。
