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[双能X线吸收法检测外源性脂肪对健康女性骨密度的正负效应]

[Positive and negative effect of exogenous fat on the bone mineral density in healthy women by dual energy X-ray absorptiometer].

作者信息

Wu Yuan, Deng Xiaoge, Jiang Shao'ai

机构信息

Department of Geriatrics, People's Hospital of Hunan Province, Changsha 410005, China.

出版信息

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Apr;35(4):365-9. doi: 10.3969/j.issn.1672-7347.2010.04.014.

Abstract

OBJECTIVE

To examine the influence of exogenous fat (lard) on the bone mineral density (BMD) of lumbar spine measured by dual energy X-ray absorptiometer (DXA) Hologic QDR 4500A in different sites in healthy women.

METHODS

Lard packets (5 cm or 10 cm thick) were prepared. The lumbar spine (LS) DXA scans were performed on 37 women(Group A), who were repeated with lard packets (5 cm or 10 cm thick) placed over the abdomen, and the hip DXA scans were performed on 18 women(Group B), who were repeated with lard packets (5 cm or 10 cm thick) placed over the left thigh. Whole body DXA scans were performed on 8 women(Group C), who were repeated with 5 cm thick lard packets over the abdomen. The pair t-test was used to compare the value of BMD with and without lard.

RESULTS

After lard was placed over abdomen, the bone area (BA), bone mineral content (BMC), and BMD of the LS decreased significantly (P<0.001);at the hip, BA had no significant change, but the BMC and BMD of the neck, trochanter, and inter trochanter increased significantly (P<0.01~0.05). The BMD of the whole body had no significant change (P>0.05).

CONCLUSION

Lard impacted the BMD by DXA Hologic QDR 4500A, BMD of the LS significantly decreases, but BMD of the whole body has no significant change. BMD of the hip significantly increases with lard.

摘要

目的

探讨外源性脂肪(猪油)对健康女性不同部位腰椎骨密度(BMD)的影响,采用双能X线吸收仪(DXA)Hologic QDR 4500A进行测量。

方法

制备不同厚度(5 cm或10 cm)的猪油包。对37名女性(A组)进行腰椎DXA扫描,在其腹部放置不同厚度(5 cm或10 cm)的猪油包后重复扫描;对18名女性(B组)进行髋部DXA扫描,在其左大腿放置不同厚度(5 cm或10 cm)的猪油包后重复扫描。对8名女性(C组)进行全身DXA扫描,在其腹部放置5 cm厚的猪油包后重复扫描。采用配对t检验比较有无猪油时的骨密度值。

结果

在腹部放置猪油后,腰椎的骨面积(BA)、骨矿物质含量(BMC)和骨密度显著降低(P<0.001);在髋部,BA无显著变化,但颈部、大转子和转子间的BMC和骨密度显著增加(P<0.01~0.05)。全身骨密度无显著变化(P>0.05)。

结论

猪油对DXA Hologic QDR 4500A测量的骨密度有影响,腰椎骨密度显著降低,但全身骨密度无显著变化。猪油使髋部骨密度显著增加。

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