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美国退伍军人炎症性肠病的流行病学

Epidemiology of inflammatory bowel disease among U.S. military veterans.

作者信息

Sonnenberg A, Wasserman I H

机构信息

Department of Biostatistics and Epidemiology, Veterans Affairs Medical Center, Milwaukee, Wisconsin.

出版信息

Gastroenterology. 1991 Jul;101(1):122-30. doi: 10.1016/0016-5085(91)90468-z.

Abstract

The Department of Veterans Affairs maintains a computerized patient treatment file that contains all records from veterans treated as inpatients in VA hospitals distributed throughout the United States. Using the patient treatment files from 1986 to 1989, the present study takes advantage of this large national data set to examine demographic and geographic associations of inflammatory bowel disease. Inflammatory bowel disease tended to affect predominantly female, white, and younger veterans, these trends being more marked in cases of Crohn's disease than ulcerative colitis. Hospital discharges secondary to both Crohn's disease and ulcerative colitis appeared to be more frequent in veterans from northern than southern parts of the United States, but did not show a seasonal variation different from the general pattern of all other diagnoses. The results in veterans confirm observations made in other studies and suggest that inflammatory bowel disease among different populations is modulated by similar pathophysiologic mechanisms and environmental risk factors.

摘要

美国退伍军人事务部保存着一个计算机化的患者治疗档案,其中包含在美国各地退伍军人事务部医院接受住院治疗的所有退伍军人的记录。本研究利用1986年至1989年的患者治疗档案,借助这个庞大的全国性数据集来研究炎症性肠病的人口统计学和地理关联。炎症性肠病往往主要影响女性、白人和较年轻的退伍军人,这些趋势在克罗恩病患者中比溃疡性结肠炎患者中更为明显。美国北部退伍军人中因克罗恩病和溃疡性结肠炎导致的住院率似乎高于南部,但与所有其他诊断的总体模式相比,并未表现出季节性变化。退伍军人中的研究结果证实了其他研究的观察结果,并表明不同人群中的炎症性肠病受相似的病理生理机制和环境风险因素的调节。

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