光控释放物从叶酸受体靶向 PAMAM 树枝状大分子纳米缀合物笼。
Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate.
机构信息
Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Medical School, Ann Arbor, MI 48109, USA.
出版信息
Chem Commun (Camb). 2010 Apr 21;46(15):2632-4. doi: 10.1039/b927215c. Epub 2010 Feb 6.
Abstract
We report the synthesis and in vitro evaluation of folate receptor-targeted nanoconjugate that releases its therapeutic payload via a photochemical mechanism.
摘要
我们报告了叶酸受体靶向纳米缀合物的合成及其体外评价，该缀合物通过光化学机制释放其治疗有效载荷。
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