对反复 IVF 失败患者的综合处理方法。
A combined approach to patients with repeated IVF failures.
机构信息
Department of Obstetrics and Gynecology, Barzilai Medical Centre, Ashkelon, Israel.
出版信息
Fertil Steril. 2010 Nov;94(6):2462-4. doi: 10.1016/j.fertnstert.2010.03.057. Epub 2010 May 7.
In an attempt to evaluate the appropriate approach in patients with repeated IVF failures, we compared the stimulation characteristics of 19 cycles. This includes the combination of diagnostic hysteroscopy and endometrial sampling during oral contraceptive pill treatment, which precedes the ultrashort GnRH-ag/GnRH-ant protocol to the patients' previous failed IVF attempt. Patients undergoing the combined approach achieved an improved outcome with reasonable implantation and clinical pregnancy rates (25 and 42%, respectively).
为了评估反复体外受精失败患者的合适方法，我们比较了 19 个周期的刺激特征。这包括在口服避孕药治疗前进行诊断性宫腔镜检查和子宫内膜取样，然后采用超短 GnRH-a/GnRH-ant 方案，这与患者之前的失败 IVF 尝试有关。采用联合方法的患者获得了更好的结局，具有合理的着床率和临床妊娠率（分别为 25%和 42%）。
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