Department of Endocrinology and Metabolism, Ajou University School of Medicine, San 5, Woncheon-Dong, Yeongtong-Gu, Suwon 443-721, Republic of Korea.
Arch Gerontol Geriatr. 2011 Jan-Feb;52(1):e19-22. doi: 10.1016/j.archger.2010.04.004. Epub 2010 May 6.
Nutrition is regarded as a major factor in the development of metabolic syndrome (MS). Undernutrition or nutritional imbalance, rather than overnutrition, can be associated with MS. We evaluated the relationship between nutritional risk and MS in the elderly. We analyzed 2284 Koreans aged over 60 years (689 men and 1595 women) from baseline data of a large prospective study called the Gwangju Dementia and Mild Cognitive Impairment Study (GDEMCIS). MS was determined according to the National Cholesterol Education Program Adult Treatment Panel III, and nutritional risk was evaluated using the Nutrition Screening Initiative (NSI) checklist. Among 2284 subjects, 1219 (53.4%) had MS. NSI score was higher in subjects with MS than in those without MS (2.46 ± 1.89 vs. 2.18 ± 1.87, p<0.001). The risks of abdominal obesity, elevated blood pressure, elevated glucose, and MS were higher in subjects with moderate or high nutritional risk compared to subjects in a good nutritional state. Nutritional risk was independently associated with MS for subjects in their 60s, but not in their 70s or 80s and above. In conclusion, high nutritional risk is associated with increased risk of MS in the elderly. Measurement of nutritional status in the elderly may serve as a marker for MS, especially for the younger elderly.
营养被认为是代谢综合征（MS）发展的一个主要因素。营养不良或营养失衡，而不是营养过剩，可能与 MS 有关。我们评估了营养风险与老年人 MS 之间的关系。我们分析了来自一项名为光州痴呆和轻度认知障碍研究（GDEMCIS）的大型前瞻性研究的基线数据中的 2284 名韩国 60 岁以上的老年人（689 名男性和 1595 名女性）。MS 根据国家胆固醇教育计划成人治疗小组 III 确定，营养风险使用营养筛查倡议（NSI）检查表进行评估。在 2284 名受试者中，有 1219 名（53.4%）患有 MS。患有 MS 的受试者的 NSI 评分高于未患有 MS 的受试者（2.46 ± 1.89 对 2.18 ± 1.87，p<0.001）。与营养状况良好的受试者相比，中重度营养风险的受试者更容易出现腹型肥胖、血压升高、血糖升高和 MS。对于 60 岁的受试者，营养风险与 MS 独立相关，但对于 70 岁或 80 岁以上的受试者则不相关。总之，高营养风险与老年人 MS 风险增加有关。测量老年人的营养状况可能是 MS 的一个标志物，特别是对于年轻的老年人。
