Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520-8063, USA.
Maturitas. 2010 Aug;66(4):389-96. doi: 10.1016/j.maturitas.2010.03.024. Epub 2010 May 6.
The average age of childbearing has been increasing in industrialized nations, including the United States. As a result, more women in their late 30s to early 40s are seeking their first pregnancy than ever before. Unfortunately, fertility declines with increasing female age. In addition, success of infertility treatments including those using assisted reproductive technologies (ART) decreases as the age of the female partner advances. Third party reproduction involves using gametes or the uterus of a third person to achieve pregnancy. Oocyte donation is a common form of third party reproduction, associated with significant success rates, which gives aging couples an opportunity to bear children. For safety and success, all the participants must be extensively screened medically and psychologically. In addition, a detailed understanding of the process by all parties involved should be achieved. While third party reproduction through oocyte donation is a long and labor intensive process with a significant amount of emotional, financial, and physical involvement from all parties, it is quite often a gratifying experience for everyone involved which include, oocyte donors, recipients, social workers, nurses and physicians.
在包括美国在内的工业化国家，女性的生育年龄呈上升趋势。因此，越来越多的女性在 30 多岁到 40 多岁时开始寻求首次怀孕。不幸的是，女性年龄的增长会导致生育能力下降。此外，随着女性伴侣年龄的增长，包括使用辅助生殖技术（ART）在内的不孕治疗的成功率也会下降。第三方生殖涉及使用第三方的配子或子宫来实现妊娠。卵母细胞捐赠是一种常见的第三方生殖形式，与显著的成功率相关，这为高龄夫妇提供了生育孩子的机会。为了安全和成功，所有参与者都必须接受广泛的医学和心理筛查。此外，还应该让所有相关方都充分了解这个过程。虽然通过卵母细胞捐赠进行第三方生殖是一个漫长而艰苦的过程，所有相关方都需要投入大量的情感、财务和身体上的精力，但这对所有相关方来说通常都是一次令人满意的经历，包括卵母细胞捐赠者、接受者、社会工作者、护士和医生。
