Infectious Diseases Institute, College of Health Sciences, Makerere University, P.O. Box 22418, Kampala, Uganda.
J Ethnopharmacol. 2010 Jul 6;130(1):43-53. doi: 10.1016/j.jep.2010.04.004. Epub 2010 May 6.
In Uganda, there are over one million people with HIV/AIDS. When advanced, this disease is characterized by life-threatening opportunistic infections. As the formal health sector struggles to confront this epidemic, new medicines from traditional sources are needed to complement control efforts. This study was conducted to document herbal medicines used in the treatment of HIV/AIDS and related opportunistic infections, and to document the existing knowledge, attitudes and practices related to HIV/AIDS recognition, control and treatment in Sembabule, Kamuli, Kabale and Gulu districts in Uganda.
In this study, 25 traditional medicine practitioners (TMPs) were interviewed using structured questionnaires.
The TMPs could recognize important signs and symptoms of HIV/AIDS and its associated opportunistic infections. The majority of practitioners treated patients who were already receiving allopathic medicines including antiretroviral drugs (ARVs) prescribed by allopathic practitioners. There were 103 species of medicinal plants identified in this survey. Priority plants identified include Aloe spp., Erythrina abyssinica, Sarcocephalus latifolius, Psorospermum febrifugum, Mangifera indica and Warburgia salutaris. There was low consensus among TMPs on the plants used. Decoctions of multiple plant species were commonly used except in Gulu where mono-preparations were common. Plant parts frequently used were leaves (33%), stem bark (23%) and root bark (18%). About 80% of preparations were administered orally in variable doses over varied time periods. The TMP had insufficient knowledge about packaging and preservation techniques.
Numerous medicinal plants for treatment of HIV/AIDS patients were identified in the four districts surveyed and the role of these plants in the management of opportunistic infections warrants further investigation as these plants may have a role in Uganda's public health approach to HIV/AIDS control.
在乌干达,有超过 100 万人感染艾滋病毒/艾滋病。当病情发展到晚期时,这种疾病的特征是危及生命的机会性感染。由于正规卫生部门努力应对这一流行病,需要从传统来源获得新的药物来补充控制工作。本研究旨在记录用于治疗艾滋病毒/艾滋病和相关机会性感染的草药,并记录乌干达 Sembabule、Kamuli、Kabale 和 Gulu 地区与艾滋病毒/艾滋病识别、控制和治疗相关的现有知识、态度和做法。
在这项研究中,我们采访了 25 名传统医学从业者(TMP),使用结构化问卷进行采访。
TMP 能够识别艾滋病毒/艾滋病及其相关机会性感染的重要体征和症状。大多数从业者治疗的患者已经接受了包括抗逆转录病毒药物(ARV)在内的全效药物治疗,这些药物是由全科医生开具的。在这次调查中,共发现 103 种药用植物。确定的重点植物包括龙舌兰属植物、非洲相思树、宽叶金合欢、退热草、芒果和卫矛。TMP 对使用的植物共识度较低。除了在 Gulu 地区,那里常见的是单一制剂,否则通常会使用多种植物的煎剂。经常使用的植物部分是叶子(33%)、茎皮(23%)和根皮(18%)。大约 80%的制剂以不同的剂量在不同的时间段内口服给药。TMP 对包装和保存技术的知识不足。
在四个调查地区发现了许多用于治疗艾滋病毒/艾滋病患者的药用植物,这些植物在治疗机会性感染方面的作用值得进一步研究,因为这些植物可能在乌干达控制艾滋病毒/艾滋病的公共卫生方法中发挥作用。