Omogbene Temitope O, Lawal Ibraheem O, Amoo Stephen O, Adam Anne A, Gebashe Fikisiwe C, Aremu Adeyemi O
School of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Westville, 4001, South Africa.
Biomedicinal Research Centre, Forestry Research Institute of Nigeria, Jericho Hill, P.M.B 5054, Ibadan, 200272, Nigeria.
Trop Med Health. 2024 Dec 26;52(1):100. doi: 10.1186/s41182-024-00651-y.
Sub-Saharan Africa faces one of the highest burdens of venereal diseases (VDs) globally. This review aims to critically evaluate the existing literature on the diverse Indigenous knowledge and medicinal plants utilised for treating VDs in sub-Saharan Africa.
We used the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) protocol to guide the execution of the review. Relevant papers from scientific databases and search engines were assessed. The inclusion criteria included literature published from 2008 and May 16, 2024, and assessment of specific predetermined VDs. Medicinal plants based on certain ethnobotanical indices and data were recorded from each literature.
Among the 131 studies included in this review, a total of 20 relevant ethnobotanical reports were identified, with Nigeria and South Africa having the highest contributions (25% each). A high diversity and richness of 445 ethnobotanically valued anti-venereal plants (99 families) from over 872 Indigenous knowledge holders were inventoried. Plants with the highest diversity of use in traditional treatment of VDs are Cassia abbreviata, Ziziphus mucronata, Ximenia caffra, Catharanthus roseus, and Terminalia prunioides. The most represented families are Fabaceae (15.8%), Cucurbitaceae (5.9%), Solanaceae (5.9%), Euphorbiaceae (5%), and Combretaceae (5%). Roots and leaves were highly utilised with frequencies of 41.5% and 26.3%, respectively. The most used method of preparation are decoctions (36.7%) and infusions (12.2%), whereas oral route (72.9%) dominated the mode of administration of the medicinal plants.
This review consolidated data from sub-Saharan Africa-notwithstanding a limited number of studies in quantitative synthesis-and identified a diverse array of ethnobotanically valued anti-venereal plants, enabling meaningful conclusions to be drawn for future ethnopharmacological assessments. Effective plant conservation and advancement of ethnobotanical research in the region require stringent regulations and cross-country collaborations.
撒哈拉以南非洲面临着全球最高的性病负担之一。本综述旨在批判性地评估关于撒哈拉以南非洲用于治疗性病的各种本土知识和药用植物的现有文献。
我们使用系统评价和Meta分析的首选报告项目（PRISMA）方案来指导综述的实施。评估了来自科学数据库和搜索引擎的相关论文。纳入标准包括2008年至2024年5月16日发表的文献，以及对特定预定性病的评估。从每篇文献中记录基于某些民族植物学指标和数据的药用植物。
在本综述纳入的131项研究中，共确定了20份相关的民族植物学报告，尼日利亚和南非的贡献最大（各占25%）。对来自872多名本土知识持有者的445种具有民族植物学价值的抗性病植物（99科）进行了编目，其具有高度的多样性和丰富性。在传统治疗性病中使用最多样化的植物是短叶决明、多毛枣、南非山梅、长春花和榄仁树。代表性最强的科是豆科（15.8%）、葫芦科（5.9%）、茄科（5.9%）、大戟科（5%）和使君子科（5%）。根和叶的利用率很高，分别为41.5%和26.3%。最常用的制备方法是煎剂（36.7%）和浸剂（12.2%），而口服途径（72.9%）在药用植物的给药方式中占主导地位。
本综述整合了撒哈拉以南非洲的数据——尽管在定量综合方面的研究数量有限——并确定了一系列具有民族植物学价值的抗性病植物，从而能够为未来的民族药理学评估得出有意义的结论。该地区有效的植物保护和民族植物学研究的推进需要严格的法规和跨国合作。
