Institute of Environment and Natural Resources, Makerere University, PO Box 7062, Kampala, Uganda.
J Ethnopharmacol. 2010 Jan 8;127(1):130-6. doi: 10.1016/j.jep.2009.09.035. Epub 2009 Sep 30.
Tuberculosis (TB) remains one of the most difficult ailments to control in the world today. The emergence of drug resistant strains has made previously effective and affordable remedies less effective. This has made the search for new medicines from local traditional medicines urgent. The specific objectives of this study were to (1) identify plant species used in the treatment of TB, their methods of preparation and administration, (2) document TB recognition, and (3) document medicine processing and packaging practices by traditional medicine practitioners (TMPs).
We interviewed 32 TMPs from the districts of Kamuli, Kisoro and Nakapiripirit using a guided questionnaire.
We documented 88 plant species used to treat TB. Seven of these, Eucalyptus spp., Warburgia salutaris (G. Bertol.) Chiov., Ocimum suave Willd., Zanthoxylum chalybeum Engl., Momordica foetida Schum., Persea americana Mill. and Acacia hockii De Wild. were mentioned by three or more TMPs. Medicines were prepared mostly as mixtures or infrequently as mono-preparations in dosage forms of decoctions and infusions. They were administered orally in variable doses over varying periods of time. The TMPs did not know how to preserve the medicines and packaged them in used water bottles. Almost all TMPs mentioned the most important signs by which TB is recognised. They also knew that TB was a contagious disease spread through poor hygiene and crowding.
Local knowledge and practices of treating TB exist in the districts surveyed. This knowledge may be imperfect and TMPs appear to be still experimenting with which species to use to treat TB. There is need to screen among the species mentioned to determine those which are efficacious and safe. The technology of processing, packaging and preserving traditional medicines for the treatment of TB is very basic and needs improving. The TMPs appear to be playing a significant role in primary health care delivery and this lends further justification for the ongoing Uganda government efforts to integrate the allopathic and traditional medicine systems.
结核病(TB)仍然是当今世界最难控制的疾病之一。耐药菌株的出现使得以前有效且负担得起的治疗方法效果降低。这使得从当地传统药物中寻找新药变得尤为迫切。本研究的具体目标是:(1)确定用于治疗结核病的植物种类、其制备和给药方法,(2)记录结核病的认识,(3)记录传统医学从业者(TMP)的药物加工和包装做法。
我们使用指导问卷采访了来自卡穆利、基索罗和纳卡皮里皮里地区的 32 名 TMP。
我们记录了 88 种用于治疗结核病的植物物种。其中有 7 种,桉树属、瓦堡西亚苏里托斯(G. Bertol。)奇奥、奥西姆苏瓦威尔德、赞特罗克斯查利贝姆恩格尔、毛罗迪达福提达舒姆、Persea americana 米利和 Acacia hockii De Wild。被 3 个或更多 TMP 提及。药物主要以混合物形式制备,或偶尔以单一制剂形式制备,剂型为煎剂和浸剂。它们以不同的剂量口服,持续不同的时间。TMP 不知道如何保存药物,而是将它们包装在旧水瓶中。几乎所有的 TMP 都提到了识别结核病的最重要的迹象。他们也知道结核病是一种通过卫生条件差和拥挤传播的传染病。
在所调查的地区存在治疗结核病的当地知识和实践。这种知识可能并不完善,TMP 似乎仍在尝试使用哪些物种来治疗结核病。有必要从提到的物种中筛选出有效和安全的物种。治疗结核病的传统药物加工、包装和保存技术非常基础,需要改进。TMP 在初级卫生保健服务中发挥着重要作用,这进一步证明了乌干达政府正在努力整合顺势疗法和传统医学系统的合理性。