Manfredini Daniele, Lobbezoo Frank
TMD Clinic, Department of Maxillofacial Surgery, University of Padova, Italy.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jun;109(6):e26-50. doi: 10.1016/j.tripleo.2010.02.013.
The present paper aims to systematically review the literature on the temporomandibular disorders (TMD)-bruxism relationship published from 1998 to 2008.
A systematic search in the National Library of Medicine's PubMed database was performed to identify all studies on humans assessing the relationship between TMD symptoms and bruxism diagnosed with any different approach. The selected articles were assessed independently by the 2 authors according to a structured reading of articles format (PICO).
A total of 46 articles were included for discussion in the review and grouped into questionnaire/self-report (n = 21), clinical assessment (n = 7), experimental (n = 7), tooth wear (n = 5), polysomnographic (n = 4), or electromyographic (n = 2) studies. In several studies, the level of evidence was negatively influenced by a low level of specificity for the assessment of the bruxism-TMD relationship, because of the low prevalence of severe TMD patients in the studied samples and because of the use of self-report diagnosis of bruxism with some potential diagnostic bias.
Investigations based on self-report or clinical bruxism diagnosis showed a positive association with TMD pain, but they are characterized by some potential bias and confounders at the diagnostic level (eg, pain as a criterion for bruxism diagnosis). Studies based on more quantitative and specific methods to diagnose bruxism showed much lower association with TMD symptoms. Anterior tooth wear was not found to be a major risk factor for TMD. Experimental sustained jaw clenching may provoke acute muscle tenderness, but it is not analogous to myogenous TMD pain, so such studies may not help clarify the clinical relationship between bruxism and TMD.
本文旨在系统回顾1998年至2008年发表的有关颞下颌关节紊乱病(TMD)与磨牙症关系的文献。
在国立医学图书馆的PubMed数据库中进行系统检索,以识别所有针对人类评估TMD症状与采用任何不同方法诊断的磨牙症之间关系的研究。两位作者根据结构化的文章阅读格式(PICO)对所选文章进行独立评估。
共有46篇文章纳入本综述进行讨论,并分为问卷调查/自我报告(n = 21)、临床评估(n = 7)、实验研究(n = 7)、牙齿磨损研究(n = 5)、多导睡眠图研究(n = 4)或肌电图研究(n = 2)。在一些研究中,由于所研究样本中重度TMD患者的患病率较低,以及使用自我报告诊断磨牙症存在一些潜在的诊断偏差,证据水平受到磨牙症与TMD关系评估特异性较低的负面影响。
基于自我报告或临床磨牙症诊断的调查显示与TMD疼痛呈正相关,但它们在诊断层面存在一些潜在偏差和混杂因素(例如,将疼痛作为磨牙症诊断标准)。基于更定量和特异方法诊断磨牙症的研究显示与TMD症状的关联要低得多。未发现前牙磨损是TMD的主要危险因素。实验性持续牙关紧闭可能会引发急性肌肉压痛,但它与肌源性TMD疼痛不同,因此此类研究可能无助于阐明磨牙症与TMD之间的临床关系。