Department of Maternal-Fetal Medicine, Institut Clínic de Ginecologia, Obstetrícia i Neonatologia, University of Barcelona, Barcelona, Spain.
Am J Obstet Gynecol. 2010 Jul;203(1):45.e1-7. doi: 10.1016/j.ajog.2010.02.044. Epub 2010 May 10.
To evaluate cardiac function by tissue Doppler imaging vs conventional echocardiography in intrauterine growth restriction.
A prospective study in 25 intrauterine growth restriction, and in 50 normally grown fetuses between 24 and 34 weeks. Conventional echocardiography (E/A ratios, outflow tract velocities and myocardial performance index), and tissue Doppler (myocardial peak velocities, E'/A' ratios and myocardial performance index') measurements were performed.
With conventional echocardiography, intrauterine growth restriction fetuses showed an increase in left myocardial performance index but similar values of E/A ratios, outflow tract velocities and right myocardial performance index as compared with controls. Tissue Doppler imaging demonstrated that intrauterine growth restriction fetuses had significantly lower systolic and diastolic myocardial velocities in mitral and tricuspid annulus, higher mitral E'/A' ratio and higher mitral, tricuspid and septal myocardial performance index' values.
Tissue Doppler imaging demonstrated the presence of both systolic and diastolic cardiac dysfunction in intrauterine growth restriction. Tissue Doppler imaging may constitute a more sensitive tool than conventional echocardiography to evaluate cardiac dysfunction in intrauterine growth restriction.
通过组织多普勒成像与传统超声心动图评估胎儿宫内生长受限的心脏功能。
这是一项在 24 至 34 周的 25 例胎儿宫内生长受限和 50 例正常生长胎儿中进行的前瞻性研究。进行了常规超声心动图（E/A 比值、流出道速度和心肌运动指数）和组织多普勒（心肌峰值速度、E'/A'比值和心肌运动指数'）测量。
与对照组相比，胎儿宫内生长受限组的左心肌运动指数增加，但 E/A 比值、流出道速度和右心肌运动指数相似。组织多普勒成像显示，胎儿宫内生长受限组的二尖瓣和三尖瓣环收缩期和舒张期心肌速度明显降低，二尖瓣 E'/A'比值升高，二尖瓣、三尖瓣和间隔心肌运动指数'值升高。
组织多普勒成像显示胎儿宫内生长受限存在收缩和舒张性心脏功能障碍。组织多普勒成像可能比传统超声心动图更能敏感地评估胎儿宫内生长受限的心脏功能障碍。
