含噻唑基的 2-氰基-3-苄基氨基丙烯酸酯的合成及除草活性。

Synthesis and herbicidal activities of 2-cyano-3-benzylaminoacrylates containing thiazole moiety.

机构信息

State Key Laboratory of Elemento-Organic Chemistry and Tianjin Key Laboratory of Pesticide Science, Nankai University, Tianjin 300071, People's Republic of China.

出版信息

Bioorg Med Chem Lett. 2010 Jun 1;20(11):3348-51. doi: 10.1016/j.bmcl.2010.04.027. Epub 2010 Apr 14.

DOI:10.1016/j.bmcl.2010.04.027

PMID:20452764

Abstract

Two series of novel 2-cyano-3-benzylaminoacrylates containing long-chain thiazole ring moiety were synthesized as herbicidal inhibitors of photosystem II (PS II) electron transportation. Their structures were confirmed by (1)H NMR and elemental analysis. The bioassay showed that these compounds retain high herbicidal activities and especially compounds 13a and 13h have excellent herbicidal activities.

摘要

合成了两个系列的新型 2-氰基-3-苄氨基丙烯酸酯类化合物，它们含有长链噻唑环部分，可用作光系统 II（PS II）电子传递的除草剂抑制剂。通过（1）H NMR 和元素分析确认了它们的结构。生物测定表明，这些化合物保留了较高的除草活性，特别是化合物 13a 和 13h 具有优异的除草活性。