Thorsteinsdóttir Lilja, Torfason Einar G, Torsteinsdóttir Sigurbjörg, Svansson Vilhjálmur
Institute for Experimental Pathology University of Iceland, Keldur v/Vesturlandsveg, IS-112 Reykjavík, Iceland.
J Vet Diagn Invest. 2010 May;22(3):420-3. doi: 10.1177/104063871002200313.
Horses are hosts to 2 types of gammaherpesviruses, Equid herpesvirus 2 and 5 (EHV-2 and EHV-5, respectively). Both EHV-2 and EHV-5 are common in horses in Iceland. An Icelandic EHV-5 isolate was recovered by sequential culture in primary fetal horse kidney and rabbit kidney cells. Glycoprotein B, glycoprotein H, and DNA terminase genes of the isolate were fully sequenced, and the DNA polymerase gene was partly sequenced. To date, the glycoprotein B gene of EHV-5 was the only gene that has been reported to be completely sequenced in addition to small parts of the glycoprotein H, DNA polymerase, and DNA terminase genes. The present report, therefore, is a significant addition to previously reported EHV-5 sequences.
马是两种γ疱疹病毒的宿主，分别为马疱疹病毒2型和5型（分别为EHV - 2和EHV - 5）。EHV - 2和EHV - 5在冰岛的马匹中都很常见。通过在原代马胎儿肾细胞和兔肾细胞中连续培养，分离出一株冰岛EHV - 5毒株。对该毒株的糖蛋白B、糖蛋白H和DNA末端酶基因进行了全序列测定，对DNA聚合酶基因进行了部分序列测定。迄今为止，除了糖蛋白H、DNA聚合酶和DNA末端酶基因的小部分序列外，EHV - 5的糖蛋白B基因是唯一已报道的完全测序的基因。因此，本报告是对先前报道的EHV - 5序列的重要补充。
