Antic Darko, Elezovic Ivo, Bogdanovic Andrija, Vukovic Nada Suvajdzic, Pavlovic Aleksandra, Jovanovic Maja Perunicic, Jakovic Ljubomir, Kraguljac Nada
Institute of Hematology, Clinical Center Serbia, Belgrade.
Intern Med. 2010;49(9):853-6. doi: 10.2169/internalmedicine.49.2874. Epub 2010 Apr 30.
Myeloid sarcoma (MS) is a rare disease that presents as an extramedullary tumor of myeloid cells. Most patients subsequently develop acute myelogenous leukemia (AML), and their prognosis is poor. Here, we report the case of a 28-year-old woman with a primary isolated myeloid sarcoma which originated in the gastrointestinal (GI) tract. Two months after initial presentation, bone marrow tests led to a diagnosis of AML. This case is noteworthy because GI tract infiltration with leukemic cells is very rare, and it is even more rare as an occurrence preceding the development of systemic leukemia.
髓系肉瘤(MS)是一种罕见疾病,表现为髓系细胞的髓外肿瘤。大多数患者随后会发展为急性髓系白血病(AML),且预后较差。在此,我们报告一例28岁女性原发性孤立性髓系肉瘤病例,该肉瘤起源于胃肠道(GI)。初次就诊两个月后,骨髓检查确诊为AML。该病例值得关注,因为白血病细胞浸润胃肠道非常罕见,而在系统性白血病发生之前出现这种情况则更为罕见。