Department of Obstetrics and Gynaecology, La Fe University Hospital, Valencia, Spain.
Fetal Diagn Ther. 2010;27(4):227-30. doi: 10.1159/000314687. Epub 2010 May 10.
Uterine malformations and spontaneous triplet pregnancy are rare situations separately, and both are related to worse perinatal outcomes. In the 3 cases of combined triplet pregnancy and uterus didelphys previously published, at least 2 of the 3 fetuses died. Morbidity rates are also high. We report the case of a 24-year-old Caucasian woman with a uterus didelphys and two previous caesarean sections who carried a spontaneous triplet pregnancy. To our knowledge, this is the first case of a spontaneous triplet pregnancy in a uterus didelphys ever reported and the only one with uneventful perinatal outcome for all fetuses. Expectant management may be an alternative to embryo reduction to manage triplet pregnancies in a didelphys uterus, especially when this option is not considered. Nevertheless, there is not enough evidence to confirm which is the optimal management strategy, and more studies are needed.
子宫畸形和自发性三胞胎妊娠分别是罕见的情况,两者都与更差的围产期结局有关。在之前发表的 3 例合并三胞胎妊娠和双子宫的病例中,至少有 2 例胎儿死亡。发病率也很高。我们报告了一例 24 岁的白人妇女,她有双子宫和两次剖宫产史,自发性三胞胎妊娠。据我们所知,这是首例报告的双子宫自发性三胞胎妊娠病例,也是唯一一例所有胎儿均无围产期不良结局的病例。期待治疗可能是减少胚胎数量以管理双子宫三胞胎妊娠的一种替代方法,特别是在不考虑这种方法的情况下。然而,目前还没有足够的证据来确认哪种管理策略是最佳的,需要更多的研究。