Ecole doctorale de Santé Publique, Faculté de médecine Paris VI, Université Pierre et Marie Curie, Paris, France.
Eur Addict Res. 2010;16(3):162-9. doi: 10.1159/000314360. Epub 2010 May 7.
We addressed the understudied topic of cessation interventions for adult light smokers (< or =10 cigarettes daily). We identified cessation aids offered in French cessation services and their impact on cessation outcomes at 1-month follow-up.
We retrospectively analyzed data from 36,594 smokers in cessation services nationwide. Smokers could be offered pharmacotherapy as well as cognitive behavioral therapy (CBT). Bivariate methods and multivariate logistic regression analyses were used.
Light smokers were 1.23 times more likely to drop out than heavy smokers. 13.3% were abstinent at follow-up versus 14.5% for heavy smokers (p = 0.013). Light smokers were offered pharmacotherapy less often than heavy smokers. Yet, among light smokers, varenicline doubled the odds of abstinence as did nicotine patch. CBT improved abstinence only when combined with nicotine patch. Intervention outcomes differed according to various profiles: light smokers self-referred or with several previous quit attempts achieved better outcomes than those not interested in quitting or referred through hospitalization.
Light smokers' poor intervention outcomes might partly be explained by inadequate treatment plans in French cessation services. Our results reveal that pharmacotherapy is effective and that tailored CBT should be offered according to the variety of profiles among light smokers.
我们研究了成人轻度吸烟者（每天吸烟<或=10 支）的戒烟干预措施这一研究较少的课题。我们确定了法国戒烟服务中提供的戒烟辅助手段，以及它们对戒烟 1 个月后结果的影响。
我们对全国范围内 36594 名戒烟服务吸烟者进行了回顾性数据分析。吸烟者可以接受药物治疗和认知行为疗法（CBT）。我们使用了双变量方法和多变量逻辑回归分析。
与重度吸烟者相比，轻度吸烟者的戒烟率低 1.23 倍。与重度吸烟者（14.5%）相比，轻度吸烟者在随访时有 13.3%的人已经戒烟（p=0.013）。与重度吸烟者相比，轻度吸烟者较少接受药物治疗。然而，在轻度吸烟者中，文拉法辛使戒烟的几率增加了一倍，尼古丁贴片也是如此。只有当 CBT 与尼古丁贴片联合使用时，才会改善戒烟效果。干预结果因各种因素而异：轻度吸烟者自行就诊或有多次戒烟尝试的戒烟效果要好于那些没有戒烟意愿或因住院而就诊的吸烟者。
法国戒烟服务中的治疗计划不足可能部分解释了轻度吸烟者较差的干预效果。我们的研究结果表明，药物治疗是有效的，应根据轻度吸烟者的各种情况提供量身定制的 CBT。
