特发性震颤中手臂摆动减少的定量分析。
Quantitative analysis of reduced arm swing frequency in essential tremor.
机构信息
Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey. drgulcinbenbir @ yahoo.com
出版信息
Eur Neurol. 2010;63(5):302-6. doi: 10.1159/000304194. Epub 2010 May 7.
BACKGROUND
Essential tremor (ET) has recently been accepted as a heterogeneous disorder which may be associated with synuclein pathology or a variety of other genetic disorders.
METHODS
We observed decreased arm swing frequency in 18 of 136 definite ET patients, and recorded the associated arm movements in 18 ET patients and 33 sex- and age-matched healthy controls.
RESULTS
The mean frequency of the right arm (p = 0.047), left arm (p = 0.025) and leg (p = 0.030), and the mean arm/leg frequency on the right side (p = 0.048) were significantly lower in ET patients. The mean frequencies for both arms and legs were significantly lower for the more affected side of the body (p = 0.034 and p = 0.036, respectively).
CONCLUSION
We conclude that ET may be associated with decreased arm and leg swing frequencies, especially on the more affected side of the body.
背景
特发性震颤（ET）最近被认为是一种异质性疾病，可能与突触核蛋白病理或多种其他遗传疾病有关。
方法
我们观察到 136 例明确 ET 患者中有 18 例手臂摆动频率降低，并记录了 18 例 ET 患者和 33 名性别和年龄匹配的健康对照者的相关手臂运动。
结果
ET 患者的右臂（p = 0.047）、左臂（p = 0.025）和腿（p = 0.030）的平均频率以及右侧手臂/腿的平均频率（p = 0.048）明显较低。身体受影响更严重一侧的双臂和双腿的平均频率明显较低（分别为 p = 0.034 和 p = 0.036）。
结论
我们得出结论，ET 可能与手臂和腿部摆动频率降低有关，尤其是在身体受影响更严重的一侧。
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