使用串联分流阀系统控制脑脊液流动和颅内压的新方法。
Novel method for controlling cerebrospinal fluid flow and intracranial pressure by use of a tandem shunt valve system.
作者信息
Aihara Yasuo, Kawamata Takakazu, Mitsuyama Tetsuryu, Hori Tomokatsu, Okada Yoshikazu
机构信息
Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan.
出版信息
Pediatr Neurosurg. 2010;46(1):12-8. doi: 10.1159/000314052. Epub 2010 May 5.
OBJECTIVE
Programmable shunt valve systems have improved the management of patients with hydrocephalus. However, associated problems such as over-drainage and slit-like ventricles, even in patients with anti-siphon devices installed, still remain unresolved.
METHODS
We conceived a novel tandem shunt valve system to overcome the problems with existing shunt valve systems. Experiments were performed in vitro and a manometer was used to measure the results.
RESULTS
Manometric measurements in vitro with the tandem shunt valve system demonstrated that it effectively controlled the final pressure under varying flow rates. This novel system was applied to 2 intractable cases (over-drainage and slit-like ventricles) with good results.
INTERPRETATION
The tandem shunt valve system has therapeutic potential not only for over-drainage and slit-like ventricles, but also for uncontrollable hydrocephalus, by precisely controlling the cerebral spinal fluid flow rate.
目的
可编程分流阀系统改善了脑积水患者的治疗管理。然而，即使在安装了抗虹吸装置的患者中，诸如过度引流和裂隙样脑室等相关问题仍未得到解决。
方法
我们构思了一种新型串联分流阀系统，以克服现有分流阀系统存在的问题。进行了体外实验，并使用压力计测量结果。
结果
串联分流阀系统的体外压力测量表明，它能在不同流速下有效控制最终压力。这种新型系统应用于2例难治性病例（过度引流和裂隙样脑室），效果良好。
解读
串联分流阀系统通过精确控制脑脊液流速，不仅对过度引流和裂隙样脑室具有治疗潜力，而且对难以控制的脑积水也具有治疗潜力。
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