School of Engineering and Applied Sciences/Department of Physics, Harvard University, Cambridge, Massachusetts, USA.
Lab Chip. 2010 Jun 21;10(12):1521-4. doi: 10.1039/c004050a. Epub 2010 May 7.
Microfluidic devices can be molded easily from PDMS using soft lithography. However, the softness of the resulting microchannels makes it difficult to photolithographically pattern their surface properties, as is needed for applications such as double emulsification. We introduce a new patterning method for PDMS devices, using integrated oxygen reservoirs fabricated simultaneously with the microfluidic channels, which serve as "chemo-masks". Oxygen diffuses through the PDMS to the nearby channel segments and there inhibits functional polymer growth; by placement of the chemo-masks, we thus control the polymerization pattern. This patterning method is simple, scalable, and compatible with a variety of surface chemistries.
微流控器件可以使用软光刻技术轻松地从 PDMS 模制而成。然而，所得微通道的柔软性使得难以对其表面性能进行光刻图案化，这对于例如双乳液化等应用是必需的。我们介绍了一种用于 PDMS 器件的新图案化方法，该方法使用与微流道同时制造的集成氧气储存器作为“化学掩模”。氧气通过 PDMS 扩散到附近的通道段，并在那里抑制功能聚合物的生长；通过放置化学掩模，我们可以控制聚合图案。这种图案化方法简单、可扩展并且与各种表面化学兼容。
