Pickartz Tilman, Mayerle Julia, Kraft Matthias, Evert Matthias, Evert Katja, Kühn Jens-Peter, Heidecke Claus-Dieter, Lerch Markus M
Klinik und Poliklinik für Innere Medizin A, Ernst-Moritz-Arndt-Universität Greifswald, Greifswald, Germany.
Med Klin (Munich). 2010 Apr;105(4):281-5. doi: 10.1007/s00063-010-1042-6.
Patients with chronic pancreatitis are burdened with an increased risk of developing pancreatic cancer. Strategies or guidelines for the surveillance and early detection of pancreatic adenocarcinoma in patients with chronic pancreatitis are not established, because available clinical, serologic or imaging techniques are still of limited sensitivity and specificity. Despite these limitations do patients with chronic pancreatitis and suspected pancreatic cancer need a careful and sometimes repeated diagnostic work-up. A clear benefit of surveillance programs outside of clinical trials for the early detection of pancreatic cancer has not been demonstrated. A 51-year-old patient with chronic pancreatitis is reported who developed cancer of the pancreatic head while undergoing repeated imaging studies.
慢性胰腺炎患者患胰腺癌的风险增加。由于现有的临床、血清学或影像学技术的敏感性和特异性仍然有限，因此尚未建立针对慢性胰腺炎患者胰腺腺癌监测和早期检测的策略或指南。尽管存在这些局限性，但慢性胰腺炎和疑似胰腺癌患者仍需要仔细且有时是反复的诊断检查。尚未证明在临床试验之外的监测计划对早期检测胰腺癌有明显益处。本文报道了一名51岁的慢性胰腺炎患者，该患者在接受反复影像学检查时发生了胰头癌。
