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首发精神分裂谱系障碍患者治疗最初 2 年的自杀倾向过程及预测因素。

Course and predictors of suicidality over the first two years of treatment in first-episode schizophrenia spectrum psychosis.

机构信息

Clinic for Mental Health and Addiction, Department of Psychiatry, University of Oslo, Oslo University Hospital, Kirkeveien 166, Oslo, Norway.

出版信息

Arch Suicide Res. 2010;14(2):158-70. doi: 10.1080/13811111003704787.

DOI:10.1080/13811111003704787
PMID:20455151
Abstract

The objective of this study was to investigate the course of suicidal behavior over the first 2 years of comprehensive, integrated treatment in two groups of patients with DSM-IV first episode schizophrenia spectrum psychosis, where one group was recruited through an early detection program. We have previously shown that the rate of severe suicidal behavior was lower in the earlier detected group than in the other. First episode schizophrenia is a high risk period for suicidality, but we found low rates of completed suicides and suicide attempts in both groups after 2 years in treatment, with no between-groups differences. Severe suicidality (plans and attempts) was predicted by drug abuse, dissatisfaction with life and severe suicidality at start of treatment.

摘要

本研究旨在探讨两组首发精神分裂症谱系障碍患者在接受综合、整合治疗的前 2 年中自杀行为的进程,其中一组是通过早期发现计划招募的。我们之前已经表明,在早期发现组中严重自杀行为的发生率低于另一组。首发精神分裂症是自杀风险较高的时期,但我们发现两组患者在接受 2 年治疗后自杀率和自杀企图率均较低,两组之间无差异。严重自杀性(计划和企图)可由药物滥用、对生活不满和治疗开始时严重自杀性预测。

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