Dipartimento di Arboricoltura, Botanica e Patologia Vegetale (ArBoPaVe), Università di Napoli Federico II, Portici, Napoli, Italy 80138.
Annu Rev Phytopathol. 2010;48:395-417. doi: 10.1146/annurev-phyto-073009-114314.
Structural and functional genomics investigations are making an important impact on the current understanding and application of microbial agents used for plant disease control. Here, we review the case of Trichoderma spp., the most widely applied biocontrol fungi, which have been extensively studied using a variety of research approaches, including genomics, transcriptomics, proteomics, metabolomics, etc. Known for almost a century for their beneficial effects on plants and the soil, these fungi are the subject of investigations that represent a successful case of translational research, in which 'omics-generated novel understanding is directly translated in to new or improved crop treatments and management methods. We present an overview of the latest discoveries on the Trichoderma expressome and metabolome, of the complex and diverse biotic interactions established in nature by these microbes, and of their proven or potential importance to agriculture and industry.
结构和功能基因组学的研究正在对当前用于植物病害防治的微生物制剂的理解和应用产生重要影响。在这里，我们回顾了 Trichoderma spp. 的案例，这是应用最广泛的生防真菌，它已经通过多种研究方法进行了广泛的研究，包括基因组学、转录组学、蛋白质组学、代谢组学等。这些真菌几乎一个世纪以来都因其对植物和土壤的有益作用而被人们所熟知，它们是转化研究的成功案例，其中“组学”产生的新认识直接转化为新的或改进的作物处理和管理方法。我们概述了 Trichoderma 表达组和代谢组的最新发现，以及这些微生物在自然界中建立的复杂多样的生物相互作用，以及它们对农业和工业的已知或潜在重要性。
