坦桑尼亚眼表鳞状上皮肿瘤的流行病学与管理
Epidemiology and management of ocular surface squamous neoplasia in Tanzania.
作者信息
Furahini Godfrey, Lewallen Susan
机构信息
Kilimanjaro Christian Medical Center Hospital Eye Department, Tumaini University, Moshi, Tanzania.
出版信息
Ophthalmic Epidemiol. 2010 Jun;17(3):171-6. doi: 10.3109/09286581003731544.
PURPOSE
To estimate the incidence of suspected ocular surface squamous neoplasia (OSSN) by Region in Tanzania and learn where these lesions are treated.
METHODS
We performed an analysis of existing theater records from three Tanzanian referral hospitals from 2006 to 2008 plus a prospective analysis of records from all other eye health workers who remove suspected OSSN outside the referral hospitals over 1 year.
RESULTS
Approximately 40% of suspected OSSN are operated on outside of referral hospitals. The estimated annual incidence of ocular surface squamous neoplasia in Tanzania was 2.2 per 100,000 persons. Regional incidence rates were significantly correlated with Regional HIV (Human immunodeficiency virus) prevalence (Pearson's r = 0.53, P = 0.03).
CONCLUSION
The incidence rate is high, in line with estimates from other East African countries. Management of these cases requires improvement as most patients are still not tested for HIV.
目的
评估坦桑尼亚各地区疑似眼表鳞状上皮肿瘤（OSSN）的发病率，并了解这些病变的治疗地点。
方法
我们对2006年至2008年坦桑尼亚三家转诊医院的现有手术记录进行了分析，并对所有其他在转诊医院以外切除疑似OSSN的眼科保健工作者的记录进行了为期1年的前瞻性分析。
结果
约40%的疑似OSSN在转诊医院以外进行手术。坦桑尼亚眼表鳞状上皮肿瘤的估计年发病率为每10万人2.2例。地区发病率与地区艾滋病毒（人类免疫缺陷病毒）流行率显著相关（Pearson相关系数r = 0.53，P = 0.03）。
结论
发病率较高，与其他东非国家的估计相符。由于大多数患者仍未接受艾滋病毒检测，这些病例的管理需要改进。
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