Sadeghian Hakimeh, Ahmadi Farzaneh, Lotfi-Tokaldany Masoumeh, Salehi Rezvanyieh, Zavar Reyhane, Fathollahi Mahmood Sheikh, Abbasi Seyed Hesameddin
Echocardiography Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Echocardiography. 2010 Aug;27(7):803-8. doi: 10.1111/j.1540-8175.2010.01154.x.
Longitudinal myocardial tissue velocity imaging (TVI) and strain rate imaging (SRI) quantify regional myocardial function. We aimed to measure TVI and SRI indices for inferobasal aneurysmal segments by echocardiography at rest.
Sixteen patients with inferobasal left ventricular (LV) aneurysm, LV ejection fraction (EF) ≤50%, and 14 normal coronaries with normal echocardiography (control group) were studied. In SRI, peak systolic strain (ST), strain rate (SR), and pattern of strain curves and in TVI, peak systolic inward motion (Sm) were evaluated all at rest. Ascending curve means systolic expansion and descending means shortening.
LVEF was significantly lower in the patient group. Mean ST, SR, and Sm of inferobasal segment showed significant difference between patient and control groups; for ST: 1.45 ± 7.18% versus -17.64 ± 7.45%, P < 0.0001; SR: -0.25 ± 0.26 versus -1.44 ± 0.64 sec(-1) , P < 0.0001; and Sm: 3.85 ± 1.26 versus 5.56 ± 1.28 cm/sec, P = 0.006, respectively. All inferobasal aneurysmal segments had ascending curve while normal segments showed a descending curve. In patient group, aneurysmal segments had significantly reduced ST and SR compared to normal segments. Normal functioning segments of patients showed significant reduction of ST and SR compared to normal LV segments in control subjects. The range of SR and ST for inferobasal aneurysmal segments did not overlap with that of the normal segments (-0.60, 0.19 and -3.00, -0.80 sec(-1) for SR, and -8.30, 23.30 and -35.30, -10.00% for ST, respectively).
SRI indices were significantly reduced in inferobasal aneurysmal segment in comparison with either the same segment in normal subjects or normal functioning segments in the same patients. SR and ST may be superior to Sm in the evaluation of inferobasal aneurysmal segments.
纵向心肌组织速度成像（TVI）和应变率成像（SRI）可量化局部心肌功能。我们旨在通过静息状态下的超声心动图测量下基底动脉瘤节段的TVI和SRI指标。
研究了16例下基底左心室（LV）动脉瘤患者，左心室射血分数（EF）≤50%，以及14例超声心动图正常的正常冠状动脉患者（对照组）。在SRI中，评估静息状态下的峰值收缩期应变（ST）、应变率（SR）和应变曲线模式，在TVI中，评估峰值收缩期内向运动（Sm）。上升曲线表示收缩期扩张，下降曲线表示缩短。
患者组的左心室射血分数显著降低。下基底节段的平均ST、SR和Sm在患者组和对照组之间存在显著差异；ST：1.45±7.18%对-17.64±7.45%，P<0.0001；SR：-0.25±0.26对-1.44±0.64秒-1，P<0.0001；Sm：3.85±1.26对5.56±1.28厘米/秒，P = 0.006。所有下基底动脉瘤节段均为上升曲线，而正常节段为下降曲线。在患者组中，动脉瘤节段的ST和SR与正常节段相比显著降低。患者的正常功能节段与对照组的正常左心室节段相比，ST和SR显著降低。下基底动脉瘤节段的SR和ST范围与正常节段不重叠（SR分别为-0.60, 0.19和-3.00, -0.80秒-1，ST分别为-8.30, 23.30和-35.30, -10.00%）。
与正常受试者的同一节段或同一患者的正常功能节段相比，下基底动脉瘤节段的SRI指标显著降低。在评估下基底动脉瘤节段时，SR和ST可能优于Sm。
