Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, School of Medicine, University of Rome Tor Vergata, Rome, Italy.
Forensic Sci Int Genet. 2010 Oct;4(5):e131-3. doi: 10.1016/j.fsigen.2010.01.017. Epub 2010 Feb 20.
Allele and genotype frequencies of 25 SNPs previously selected and validated for forensic purposes were assessed in 250 unrelated individuals originating from five different countries of Europe (Spain, Croatia, Bulgaria, Turkey and Serbia). All the SNPs generated extremely low F(st) values confirming our previous results on Italian, African (Benin) and Asian (Mongolian) populations. As a consequence of such F(st) values we observed similar values of random match probability across the populations: 2.26 x 10(-10) in the Spanish population, 2.13 x 10(-10) in the Croatian population, 4.21 x 10(-10) in the Bulgarian population, 2.52 x 10(-10) in the Serbian population and 1.46 x 10(-10) in the Turkish population.
在来自欧洲五个不同国家(西班牙、克罗地亚、保加利亚、土耳其和塞尔维亚)的 250 个无关个体中,评估了先前为法医学目的选择和验证的 25 个 SNP 的等位基因和基因型频率。所有产生的 SNP 都产生了极低的 F(st) 值,证实了我们之前对意大利、非洲(贝宁)和亚洲(蒙古)人群的研究结果。由于这些 F(st) 值,我们观察到了不同人群中随机匹配概率的相似值:在西班牙人群中为 2.26 x 10(-10),在克罗地亚人群中为 2.13 x 10(-10),在保加利亚人群中为 4.21 x 10(-10),在塞尔维亚人群中为 2.52 x 10(-10),在土耳其人群中为 1.46 x 10(-10)。