Breast Imaging and Interventional Center, Department of Radiology, The George Washington University, 2150 Pennsylvania Avenue NW, Washington, DC 20037, USA.
Acad Radiol. 2010 Jun;17(6):735-43. doi: 10.1016/j.acra.2010.01.017.
The aim of this study was to determine how often breast-specific gamma imaging (BSGI) identifies occult cancerous lesions in women with one suspicious lesion detected on mammography or physical exam.
A retrospective review was performed of the records of all patients who underwent BSGI between January 1, 2004, and June 4, 2007. Included in the study were 159 women who had one suspicious breast lesion on physical exam and/or mammography and who underwent BSGI to evaluate for occult lesions in the breast. All patients had one or more foci of cancer proven pathologically. BSGI findings were classified as normal or abnormal on the basis of the presence of focal radiotracer uptake.
BSGI detected additional suspicious lesions occult to mammography and physical exam in 46 of 159 women (29%). BSGI identified occult cancer in 14 of 40 women (35%) who underwent biopsy or excision because of BSGI findings and in 14 of the 159 (9%) women in this study. In nine women, the occult cancer was present in the same breast as the index lesion (6%), and in five women, the occult cancer was found in the contralateral breast (3%).
BSGI is an effective imaging modality in the identification of mammographically and clinically occult cancer in women with one suspicious breast lesion.
本研究旨在确定乳腺特异性伽马成像（BSGI）在乳腺触诊或 X 线检查发现一个可疑病灶的女性中，发现隐匿性癌性病变的频率。
回顾性分析了 2004 年 1 月 1 日至 2007 年 6 月 4 日期间所有接受 BSGI 检查的患者的记录。研究纳入了 159 例乳腺触诊和/或 X 线检查发现一个可疑病灶且接受 BSGI 检查以评估乳腺隐匿性病灶的女性。所有患者均有一个或多个病灶经病理证实为癌症。根据放射性示踪剂摄取的存在，将 BSGI 结果分类为正常或异常。
BSGI 在 46/159（29%）例女性中发现了乳腺触诊和 X 线检查隐匿的可疑病灶。BSGI 在 40/159（25%）例因 BSGI 结果而行活检或切除的女性中发现了隐匿性癌，在本研究的 159 例女性中发现了 14/159（9%）例隐匿性癌。在 9 例女性中，隐匿性癌与索引病灶位于同一乳房（6%），在 5 例女性中，隐匿性癌位于对侧乳房（3%）。
BSGI 是一种有效的影像学方法，可在乳腺触诊和 X 线检查发现一个可疑病灶的女性中识别隐匿性乳腺癌。
